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Pharmacokinetic Profiling in Drug Research

success of the previous work ( Pharmacokinetic Optimization in Drug Research: Biological, Physicochemical, and Computational Strategies , Eds. B;

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Hit and Lead Profiling

The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be;

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Lead Optimization for Medicinal Chemists

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a;

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Preclinical Drug Development

Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from;

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Basic Pharmacokinetics

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It;

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as;

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Pharmacokinetic Challenges in Drug Discovery

drug discovery process. One of the biggest challenges is the pharmacokinetic (PK) optimisation of drug candidates tailored and predicted to;

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Clinical Pharmacokinetics

. Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles;

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Biomarkers in Clinical Drug Development

Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference;

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Molecular Drug Properties: Measurement and Prediction

on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those;

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Handbook of Pharmacokinetic/Pharmacodynamic Correlation

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and;

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Handbook of Pharmacokinetic/Pharmacodynamic Correlation

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and;

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Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition

performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field's leading text for more than three;

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Physiologically Based Pharmacokinetic (PBPK) Model ing and Simulations

physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics;

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Clinical Pharmacokinetics

This is the fourth edition of Clinical Pharmacokinetics . The book is written for clinicians with experience in basic pharmacokinetic;

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Transporters in Drug Discovery and Development

and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic;

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Pharmacokinetics in Drug Discovery and Development

areas. Fulfilling the need for a wide-ranging guide to the many existing subspecialties in this field, Pharmacokinetics in Drug Discovery and;

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Target Discovery and Validation

The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and;

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Drug Delivery Approaches - Perspectives from Pharmacokinetics and Pharmacodynamics

by leading experts in the field Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics delivers a thorough;

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Protease Inhibitors in AIDS Therapy

by success stories of pharmaceutical companies and biotechnology start-up firms summarizes the pharmacokinetics, metabolism, and drug;

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Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics

drug applications. Key updates reflect advances in PK/PD as related to clinical decision-making and drug research and development. An;

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Kinase Screening and Profiling

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug;

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Essential Pharmacokinetics

theoretical background of pharmacokinetic behavior of drugs and excipients.Shows how to apply basic pharmacokinetic methods to evaluate drugs;

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Enzyme Inhibition in Drug Discovery and Development

pharmacology and pharmacokinetic aspects of enzyme inhibition. Additionally, the book covers the inhibition of drug metabolizing and disposition;

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Drug Toxicity and Metabolism in Pediatrics

The aim of this text is to examine the physiological development of the fetus. It allows the reader to study the unique pharmacokinetic and;

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Pharmacokinetics

This book is based on research papers and commentaries on pharmacokinetic methods and applications published since 1975. It offers detailed;

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New Horizons in Predictive Drug Metabolism and Pharmacokinetics

Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically;

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