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medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic;
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strategies, including lead optimization starting from high throughput screening hits as well as rational, structure-based design. The chapters;
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Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization;
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This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as;
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Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful;
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is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures;
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and tropical diseases. The result is a prime knowledge resource for medicinal chemists and for every scientist involved in lead generation.;
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discovery scientists, the book is organized according to the various strategies deployed for the discovery and optimization of initial lead;
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the reader can find more detail on specific topics of interest if required. Medicinal Chemistry is essential reading for students studying;
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Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal;
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A Single Source on Parallel Synthesis for Lead Optimization The end of the previous millennium saw an explosion in the application;
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work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It;
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work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It;
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With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to;
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evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling;
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resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery. Reviews the key;
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The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a;
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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an;
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Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery;
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, current methods, and future prospects, the coverage addresses novice medicinal chemists, providing them with a jump-start to their understanding;
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of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures;
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.* A must-to-have resource for all synthetic chemists working in drug development and medicinal chemistry* Makes use of the leading reagent;
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products and from pharmaceutical industries. It is a valuable source for all people engaged in the study of medicinal plants.;
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. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic;
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Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to;
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correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical;
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Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores;
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