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Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can;
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bioavailability one of the most significant hurdles in drug discovery and development. Describes approaches to assess pharmacokinetics and how drug efflux;
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need to be considered when developing a new drug. The book details steps in the preclinical process including: prioritizing and optimizing;
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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can;
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sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost;
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and clinical drug development process.;
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of preclinical pharmacology, toxicology, and model-based approaches for biologic drug development and the risk of drug-drug interactions.;
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microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox;
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resource for practitioners in drug discovery and development, preclinical and clinical researchers, toxicologists and pharmacologists, molecular;
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This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create;
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accelerate drug development. Various topics within tracer development, instrumentation, data analysis and many clinical and preclinical topics are;
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computational tools for drug discovery and development, with new translational approaches to clinical drug investigations in various human populations;
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hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project;
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of drug target discovery to drug discovery, development, and testing in preclinical and clinical models. Topics include drug lead screening, drug;
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This book overviews in vivo imaging techniques for both the development of drug delivery systems and controlled release dosages. Written by;
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This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront;
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translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development;
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. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety;
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methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples;
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to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects * Contains;
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drugs and their development through in vitro, involving tissues and cell lines, and in vivo models, using animals as experimental systems;
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, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use;
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Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary;
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To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new excipients to be developed;
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