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) is key in drug development. This is an enlightening reference for scientists, medicinal chemists, and others working in drug discovery.;
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preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning;
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bioavailability one of the most significant hurdles in drug discovery and development. Describes approaches to assess pharmacokinetics and how drug efflux;
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hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project;
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Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from;
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areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical;
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detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development;
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This book overviews in vivo imaging techniques for both the development of drug delivery systems and controlled release dosages. Written by;
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candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront;
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To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new excipients to be developed;
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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can;
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. This book covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on novel molecular targets;
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Applications of Microdialysis in Pharmaceutical Science focuses on the use of microdialysis in drug evaluation for different organs and;
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of preclinical pharmacology, toxicology, and model-based approaches for biologic drug development and the risk of drug-drug interactions.;
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for human disease - as one way to improve cancer drug development and reduce attrition of investigational agents. Tumors that spontaneously;
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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can;
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resource for practitioners in drug discovery and development, preclinical and clinical researchers, toxicologists and pharmacologists, molecular;
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reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate;
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need to be considered when developing a new drug. The book details steps in the preclinical process including: prioritizing and optimizing;
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Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates in a wide category;
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Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates in a wide category;
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. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory;
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This book is useful to readers who are just beginning in the field of drug design and development. It starts with an introduction and some;
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Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both;
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