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metabolic features of newborns and gives specific examples of drug metabolism in the newborn. The purpose of this book is to enhance the current;
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This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1;
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of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair Introduces new;
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evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling;
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Human Drug Metabolism, An Introduction, Second Editionprovides an accessible introduction to the subject and will beparticularly invaluable;
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toxicology, biomolecular sciences, biochemistry, genetics, environmental biomonitoring, drug metabolism and carcinogenesis.;
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Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically;
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of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable;
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on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism;
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A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental;
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, metabolism, and excretion, potential for hepatic and renal toxicity, immunogenicity of biotherapeutics and translational tools for predicting human;
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bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and;
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in which PET offers new and unique information for the development of drugs (conception, toxicity, pharmacokinetics and metabolism, clinical;
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toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are;
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available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint;
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available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint;
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, including the study of drug metabolism and toxicity. Aimed at NMR spectroscopists, pharmacologists, imaging researchers and pharmaceutical;
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. While there are numerous resources available for understanding drug structure, and other texts relating to drug metabolism from a biological;
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book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug;
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scientists in the fields of PAH metabolism and toxicity in both aquatic and mammalian systems, this book discusses recent advances in the areas;
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This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It;
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of safety, pharmacokinetics, metabolism and toxicity of the new drug are analyzed prior to clinical trials. This book presents researches and;
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function, altered drug metabolism and multiple comorbidities. This book examines in detail the nature of renal injury in the elderly and its;
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Drug Metabolism in Psychiatry;
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The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with;
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This book offers a comprehensive overview of drug and chemical cellular toxicity, especially concerning the effects of anticancer drugs;
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This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It;
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