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Current Concepts in Drug Metabolism and Toxicology

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1;

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Evaluation of Drug Candidates for Preclinical Development

sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost;

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Drug Toxicity and Metabolism in Pediatrics

metabolic features of newborns and gives specific examples of drug metabolism in the newborn. The purpose of this book is to enhance the current;

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Lysosomes: Biology, Diseases, and Therapeutics

allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates Discusses the role;

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Human Drug Metabolism

of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable;

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Drug Metabolism in Diseases

Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states;

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Interindividual Variability in Human Drug Metabolism

The book provides an exhaustive, authoritative and updated review on the interindividual variability in drug metabolism in humans. Four;

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Preclinical Drug Development

evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling;

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A Handbook of Bioanalysis and Drug Metabolism

theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug;

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A Handbook of Bioanalysis and Drug Metabolism

theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug;

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Postmortem Toxicology of Abused Drugs

Toxicology of Abused Drugs considers the role of toxicology in the investigation of homicide, suicide, accident, natural death, and overdose. It;

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Detection of Drug Misuse

. Detection of Drug Misuse describes the current state-of-the-art techniques used for identifying and confirming drug misuse as well as recent;

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Drug Metabolism and Pharmacokinetics Quick Guide

Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages;

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Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary

and relevance to drug metabolism, Cytochromes P450 drug metabolism within the brain, Mammalian cytochrome P450 biodiversity: Physiological;

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Handbook of Drug Metabolism

framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the;

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Handbook of Drug Metabolism

framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the;

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Pharmaceutical Toxicology in Practice

testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description;

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ADME-Enabling Technologies in Drug Design and Development

tool for drug metabolism scientists and as a reference for scientists in the fields of pharmacology, medicinal chemistry, pharmaceutics;

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Mass Spectrometry in Drug Metabolism and Pharmacokinetics

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from;

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Principles of Toxicology Testing, Second Edition

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to;

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Oral Formulation Roadmap from Early Drug Discovery to Development

Covers regulatory filing, drug metabolism and physical and chemical properties, toxicology formulation, biopharmaceutics classification system;

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Clinical Ocular Toxicology

Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and;

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Toxicology and Drug Testing, An Issue of Clinics in Laboratory Medicine

toxicology. Experts will discuss common drugs in analgesia, toxicology techniques, errors and interferences in toxicology testing, toxicology;

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Drug-Like Properties

have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug;

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Drug Design Strategies

optimising potency, selectivity, drug metabolism and pharmacokinetic properties and toxicology, and the design of chemical libraries to feed the;

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Forensic Toxicology

introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics;

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New Horizons in Predictive Drug Metabolism and Pharmacokinetics

important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and pharmacokinetics. Readers;

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