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Metabolite Safety in Drug Development

A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental;

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Pharmacokinetics in Drug Development

The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug;

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Reactive Drug Metabolites

of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity;

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Quantitative Evaluation of Safety in Drug Development

Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both;

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Accelerating the Development of Biomarkers for Drug Safety

safety, and provide a more focused and rational pathway to drug development. On October 24, 2008, the IOM's Forum on Drug Discovery, Development;

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Drug Safety in Developing Countries

Drug Safety in Developing Countries: Achievements and Challenges provides comprehensive information on drug safety issues in developing;

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Genomics in Drug Discovery and Development

personnel, discovery toxicologists, and safety scientists, drug development professionals, and pharmaceutical scientists.;

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Mass Spectrometry in Drug Metabolism and Disposition

emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive;

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Handbook of Drug Metabolism

framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the;

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Handbook of Drug Metabolism

framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the;

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Cardiac Drug Safety: A Bench To Bedside Approach

safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and;

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Pharmacoepidemiology and Pharmacovigilance

safety, clinical investigators, medical evaluators and those seeking regulatory approval enhance the safety of the drug development process for;

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Drug Efficacy, Safety, and Biologics Discovery

Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D;

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Principles of CNS Drug Development

. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety;

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Evaluation of Drug Candidates for Preclinical Development

sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost;

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Emerging Safety Science

because of safety concerns between 2000 and March 2006 (GAO, 2006). Finding ways to select successful drug candidates earlier in development could;

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Nonclinical Safety Assessment

in Nonclinical Safety Assessment is written by experts who have direct, firsthand involvement in drug development in the regions where they are located;

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Hit and Lead Profiling

The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be;

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Dose Optimization in Drug Development

recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD;

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Antibody-Drug Conjugates

improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. Discusses the basics, drug delivery strategies;

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Cobert's Manual Of Drug Safety And Pharmacovigilance

Completely revised and updated, the Manual of Drug Safety and Pharmacovigilance, Second Edition is a how-to manual for those working in the;

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Imaging in Drug Discovery and Early Clinical Trials

This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target;

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Complete Accounts of Integrated Drug Discovery and Development

These engaging accounts walk readers through the drug discovery and development processes, from identification of a target compound to the;

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The Future of Drug Safety

In the wake of publicity and congressional attention to drug safety issues, the Food and Drug Administration (FDA) requested the Institute;

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Organic Chemistry of Drug Degradation

to maintaining the stability, efficacy, and safety of a drug product throughout its shelf-life. During analytical method development;

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Predictive Approaches in Drug Discovery and Development

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and;

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Advanced Concepts and Applications

Vol. 2 of Chemoinformatics of Natural Products introduces the reader to the currently available tools for toxicity prediction, drug;

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