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This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both;
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; atropisomers; case history of the insomnia drug suvorexant Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and;
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Drug Design and Discovery in Alzheimer's Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and;
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successful drug discovery. Now in a second edition, this proven work clearly explains the biochemical data and experimental details underlying the;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from;
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: In Vitro Methods and Protocols serves as a key guide for researchers in the area of discovery and development of new medicines.;
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Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti;
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further the understanding of enzyme dynamics, mechanism, inhibition, and drug design. Focuses on the recent success in structural and;
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Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages;
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Handbook of Assay Development in Drug Discovery is an ideal bench top companion for discovery researchers, laboratory managers, academics, and;
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processes and for the development of chemotherapeutic agents for the treatment of various disorders. Proteinase and Peptidase Inhibition presents;
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tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery.;
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of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development;
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importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for;
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A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research;
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various metabolic reactions. The next part examines the consequences of drug and xenobiotic metabolism in a pharmacological and toxicological;
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Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display;
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Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide;
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of enzymes. The scientific information related to the recombinant enzyme modifications, discovery of novel enzymes and development of synthetic;
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Enzyme Technologies in Drug Discovery highlights how, what, and where enzymes have become critical in pharmaceutical and biotechnology;
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aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive;
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One of the major shortcomings of the current drug discovery and development process is the inability to bridge the gap between early stage;
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From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug;
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authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies;
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studies performed by experts across the globe in the fields of drug discovery and drug development. A number of latest researches have been;
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protein evolution, aimed to identifying new receptors and natural ligands for orphan receptors , drug discovery (peptides might act as enzyme;
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