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Kinase Screening and Profiling

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug;

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Protein Kinase Inhibitors in Research and Medicine

. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad;

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Iressa-A Boon to Colon Cancer

extra cellular signal. The In-silico properties facilitate more efficient design of screening libraries and serves as a foundation for numerous;

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The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment;

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Platform Technologies in Drug Discovery and Validation

Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry;

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Protein Kinase C

comprehensive account of the fundamental structural and biochemical properties of Protein Kinase C. The remaining chapters contain overviews of the;

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Kinomics

Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging;

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A Closer Look at Kinase Inhibition

A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms;

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Kinase Inhibitor Drugs

Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the;

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Kinase Drug Discovery

Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13;

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Target Discovery and Validation

The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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Resistance to Tyrosine Kinase Inhibitors

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common;

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Advances in Veterinary Oncology, An Issue of Veterinary Clinics of North America: Small Animal Practice

This issue focuses on new advances in oncology in treating dogs and cats. Topics include: Use of metronomic chemotherapy in veterinary;

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Proteinkinase Inhibitors

This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a;

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The Value of Genetic and Genomic Technologies

Knowing one's genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic;

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Hit and Lead Profiling

screening, organ-specific toxicity assays for liver, heart, kidney and blood, as well as profiling for autoimmune reactions. By addressing both drug;

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MicroRNA Protocols

screening miRNAs in mR-302/367 induced iPSCs, exosomal miRNAs from iPSC-derived cardiomyocytes proliferation, and the recently discovered sugar-like;

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Prostate Cancer

from initial screening through novel and experimental treatments that have the potential for a major impact on practice. The book first;

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Label-Free Technologies For Drug Discovery

mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance;

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Lipidomics and Bioactive Lipids: Lipids and Cell Signaling

techniques. Articles in this volume cover topics such as Phospholipase A1 assays using a radio-labeled substrate and mass spectrometry; Real-time;

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Protein Kinases in Drug Discovery

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by;

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Targeting Protein Kinases for Cancer Therapy

This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;

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Anti-Inflammatory Drug Discovery

therapeutic targets and provides a key reference for those interested in the prosecution of modern drug discovery programs directed at anti;

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AMP-Activated Protein Kinase Signalling

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