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. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad;
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Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;
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Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;
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sensitizing agents to their research in clinical practice and in trials. Summarizes the sensitizing role of some tyrosine kinase;
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This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;
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of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;
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Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by;
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progression of many types of cancers, inflammatory disorders, and other diseases. Thus, decades of research have revealed much about how protein;
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century has seen the emergence of targeted therapy, resulting from the identification of molecular pathways in cells and their alterations;
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Advances in Medicine and Biology presents original research results on the leading edge of medicine and biology. Each article has been;
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on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment;
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significant advances in recent basic research on Protein Kinase C are explained by active researchers in the field. The first seven chapters provide a;
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This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a;
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The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common;
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Advances in Medicine and Biology presents original research results on the leading edge of medicine and biology. Each article has been;
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been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future;
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, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms;
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, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms of cancer;
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Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the;
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enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure;
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enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure;
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treatment options. Protein kinase inhibitors, currently in clinical practice and under research for potential clinical usefulness, are also reviewed;
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Advances in Medicine and Biology presents original research results on the leading edge of medicine and biology. Each article has been;
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is gradually declining, transcription factor inhibition is the next hot topic for oncology research and merits much attention. This book highlights;
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Inhibitors; Topoisomerase I Inhibitors; and New Strategies and Drugs Inhibiting Folate Pathways.;
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in cell cycle control and the study of folding/unfolding kinetics of lattice proteins by applying a simple statistical mechanical model for;
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