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This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;
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of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;
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called kinases are enzymes required by cancer cells to grow, proliferate, and survive apoptosis (death) by the immune system. Two important;
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experimental and computational methods for studying the role of protein kinases in different diseases, along with sections on the design of suitable;
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This book provides an in-depth knowledge of protein kinases. The aim of this book is to educate readers regarding protein kinases. As;
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nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal;
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discussed in this compilation include emerging targets in cancer therapy and novel nanotechnology-based therapeutic strategies that have been;
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describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune;
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of other proteins. In this way, protein kinases help monitor the extracellular environment and integrate signaling cues that, for the most part;
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unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and;
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Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells;
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Src-family, Syk-ZAP-70 family and BTK family of tyrosine kinases. 3. Regulatory GTPases, for example, the Ras protein. 4. Cytoplasmic Serine;
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-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways;
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Kumar Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes , Jeremy Murray , Domagoj Vucic The;
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Besides surgery, radiation therapy, endocrine therapy or chemotherapy, which were widely used in cancer patients for decades, the 21st;
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additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors;
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This issue, focusing on Breast Cancer, includes topics such as: Radiation Therapy for DCIS, Axillary dissection, Pathology in the age;
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This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating;
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treatment options. Protein kinase inhibitors, currently in clinical practice and under research for potential clinical usefulness, are also reviewed;
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Written by leading scientists in the field of delivery of protein and peptide drugs to tumors for cancer therapy, this important book;
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Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and;
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goal of Plant Kinases: Methods and Protocols is to provide the experimentalist with a detailed account of the practical steps necessary for;
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disorders and also cancer. Protein tyrosine phosphatases have slowly, yet convincingly become crucial targets for therapeutic intervention;
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Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector;
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therapy for cancer; epigenetic upregulation or direct over-expression of miR-137 enhances anti-tumour activity of delphinidin for inducing;
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aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology;
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