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Extracellular Targeting of Cell Signaling in Cancer

extracellular ligands (growth factors.) Both kinases are oncogenes which are required by cancer cells to migrate away from the primary tumor, invade;

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Extracellular Matrix: Pathobiology and Signaling

understanding the various facets of extracellular matrix and its interactions with cells in normal tissue as well as in disease. It represents the;

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Cell-Extracellular Matrix Interactions in Cancer

Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their;

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WNT Signaling

bind to Frizzled and LRP family receptors on the cell surface, triggering a series of events that cause ?-catenin to enter the nucleus and;

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Proteoglycans in Stem Cells

migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and;

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GPCR Signaling in Cancer

, Emerging GPCR signaling pathways in cancer, and more. G protein-coupled receptors (GPCRs) constitute a large family of cell surface;

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Targeted Cancer Imaging

extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise;

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Cancer Cell Signaling

This fully updated edition provides the most recent advances in cancer cell signaling knowledge combined with some discussion of the;

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Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and;

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Extracellular and Intracellular Signaling

Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and;

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Intracellular Signalling Proteins

, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells;

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Cancer Cell Signaling

activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a;

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Cancer Cell Signaling

activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a;

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Polyamine Cell Signaling

research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer;

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Cellular Signal Processing

view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern;

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Hedgehog signaling activation in human cancer and its clinical implications

of this pathway occurs in a variety of human cancer, including basal cell carcinomas (BCCs), medulloblastomas, leukemia, gastrointestinal, lung;

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Cancer Signaling

Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how;

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Advances in Cancer Research

pathways in tumorigenesis, hereditary diffuse gastric disease, the role of heparan sulfate proteoglycans in cell signaling and cancer, V-gene;

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Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity

negatively regulate T-cell activation . Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for;

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Animal Lectins

their potential applications to pharmacology, immunology, cancer therapy, and agriculture. With growing interest in the glycobiology field, the;

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Cellular Signal Processing

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated;

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The Cancer Degradome

functionality, homeostasis, and fate at the levels of the cell and the entire organism. For the cancer cell, intracellular prote- ysis carried out by;

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Pharmacotherapeutic Botanicals for Cancer Chemoprevention

book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.;

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Death Receptors and Cognate Ligands in Cancer

proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role;

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Analysis of Growth Factor Signaling in Embryos

extracellular signals. Finally, Section IV addresses emerging strategies that facilitate integrated analyses of cell signaling in vivo in embryonic;

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Prostate Cancer

. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression;

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Functioning of Transmembrane Receptors in Signaling Mechanisms

A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their;

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