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Protein Kinase-mediated Decisions Between Life and Death

provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions;

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Protein Kinase C

comprehensive account of the fundamental structural and biochemical properties of Protein Kinase C. The remaining chapters contain overviews of the;

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Protein Kinase Inhibitors in Research and Medicine

. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad;

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Advances in Cancer Research

of Cell Proliferation and Differentiation. Molecular Pathogenesis o f Human Hepatocellular Carcinoma. The Cell Mediated Immune Response to;

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Protein Kinases in Drug Discovery

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by;

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AMP-Activated Protein Kinase Signalling

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Next Generation Kinase Inhibitors

extracting a phosphate from the energy molecule ATP and linking it to another protein, protein kinases alter the structure and ultimate function;

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Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Huntington's disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death;

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Targeting Protein Kinases for Cancer Therapy

This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;

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A Closer Look at Kinase Inhibition

of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;

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Obesity and Cancer

of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and;

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New Developments in Proteomics Research

in cell cycle control and the study of folding/unfolding kinetics of lattice proteins by applying a simple statistical mechanical model for;

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Cognitive Dysfunctions

emerging field to diagnose cognitive discomfort and specific learning disorders; and the systemic blockade of Cav2.1 mediated NMDA receptor;

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Gadd45 Stress Sensor Genes

researchers, encode for small (18 kd) nuclear/cytoplasmic proteins). These genes are rapidly induced by a wide variety of endogenous and exogenous;

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Advances in Medicine & Biology

cardiac signalling of insulin and oestrogen hormones and protein kinase B; collaboration and conflict within maternity care; mass spectrometry;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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Zoledronic Acid Inhibits Cancer Growth

from HDM2 mediated ubiquitination and degradation by ZOL. In conclusion, this report demonstrates a critical role of the GSK3-HDM2 signaling;

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Kinase Drug Discovery

reviews areas beyond protein kinases and beyond the human kinome. Also described are modern approaches to finding kinase leads and the book;

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Advances in Medicine & Biology

mucosal hypoplasia risk factors; IkB Kinase and heat shock protein 90 complex in inflammatory response to bacterial infection; prescribing errors;

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Between Life and Death

This book aims to equip Christians facing end-of-life decisions by simplifying confusing jargon and exploring biblical principles families;

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Cell Biology and Biotechnology

Production Stimulating Factors; Erythropoietin Control of Programmed Death in Erythroid Progenitors; Prohormone Processing Enzymes and Protein;

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Protein Kinase C

drug resistance. A final review is provided which dissects the crosstalk between p53 and PKC in the context of apoptotic cell death and cancer;

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Ischemic Stroke

flow in a localized region of the brain. It represents the second cause of death and the leading cause of neurological disability in developed;

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AMPK-S6K1 Signaling Pathway as a Target for Treating Hepatic Insulin Resistance

Hepatic insulin resistance and altered insulin metabolism, as characterised by the desensitisation of hepatic parenchymal cells to insulin;

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Advances in Medicine & Biology

provision of safe blood transfusion services in a low income setting in West Africa; anticoagulant and cytoprotective protein C pathways;

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