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This book provides an in-depth knowledge of protein kinases. The aim of this book is to educate readers regarding protein kinases. As;
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Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells;
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Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by;
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Protein kinases are fascinating enzymes that maintain the proper function of nearly every task performed by the cells of the human body. By;
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; the structure of Alpha-1 proteinase inhibitor polymer; the roles of mammalian mitogen-activated protein kinase activating protein kinases;
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Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation;
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successfully carrying out each protocol in his or her own laboratory. Plant protein kinases specifically addressed in this volume are members of the;
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This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;
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Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation opens with a summary of the present knowledge about MAPK;
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loop), as well as the proliferation of neighbouring cells. There are six known classes of protein kinases and related proteins that can become;
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treatment of autoimmune diseases * The PIF-binding pocket of AGC kinases * Peptidic inhibitors of protein-protein interactions for cell adhesion;
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of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;
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of receptor desensitization, and assessment of receptor/G protein coupling); the role of regulatory proteins (receptor kinases and phosphatases;
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carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.;
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The authors consider small and poorly-studied groups of plant calcium-dependent protein kinases that directly interact with calmodulin;
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in vertebrates. Regucalcin plays a multifunctional role in cellular regulation, including an inhibitory role in protein kinases, protein phosphatases, NO;
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protein tyrosine kinases. This essential interplay between the opposing actions of protein tyrosine phosphatases and protein tyrosine kinases;
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small-compound libraries in order to find potentially suitable molecules. Protein kinases are a class of enzymes involved in the great majority;
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This volume covers various aspects of co-immunoprecipitation (co-IP) methods and its relevant use in studying protein-protein interactions;
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Integrated Methods in Protein Biochemistry: Part A, Volume 677, the latest release in the Methods in Enzymology series, highlights new;
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the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes;
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an international panel of experts in the field, the book integrates diverse aspects of biochemistry, molecular biology, protein engineering;
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in the plasma membranes of cells. The receptors of many hormones are coupled to G-protein coupled signalling pathways. Insulin and growth factors;
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kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes;
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of receptor kinases, their signaling pathways, and the ways in which these important signaling proteins are regulated.;
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G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review;
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