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Protein Kinases in Development and Disease

Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation;

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Protein Kinases in Drug Discovery

of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development;

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Next Generation Kinase Inhibitors

extracting a phosphate from the energy molecule ATP and linking it to another protein, protein kinases alter the structure and ultimate function;

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Integrated Study of Protein Kinases

globe. Existing literature is reviewed in this book, and occasionally, new data on the function of protein kinases in different systems is also;

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Protein Kinase-mediated Decisions Between Life and Death

Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells;

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A Closer Look at Kinase Inhibition

of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;

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Targeting Protein Kinases for Cancer Therapy

This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;

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Protein Tyrosine Phosphatases

protein tyrosine kinases. This essential interplay between the opposing actions of protein tyrosine phosphatases and protein tyrosine kinases;

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Receptor Tyrosine Kinases Family and Subfamilies

in development and human disease. Following are in-depth analyses of each family's receptors with discussions on the gene, protein, ligands, activation;

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Plant Kinases

plant MAP kinase cascade, cyclin- and Calcium-dependent protein kinases, and plant sensor and receptor kinases. Written in the highly successful;

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Mitogen Activated Protein Kinases

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Protein-Protein Interactions In Drug Discovery

receptors * The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases and more;

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Progress in Oncogene Research

loop), as well as the proliferation of neighbouring cells. There are six known classes of protein kinases and related proteins that can become;

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Protein-Protein Interactions in Human Disease, Part A

Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein;

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Extracellular Targeting of Cell Signaling in Cancer

, proteomics, cell biology, pharmacology, biophysics, structural biology, medicinal chemistry and drug development. A large class of proteins;

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Protein Phosphorylation in Aging and Age-Related Disease

source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An;

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New Developments in Proteomics Research

; the structure of Alpha-1 proteinase inhibitor polymer; the roles of mammalian mitogen-activated protein kinase activating protein kinases;

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Genes and Signal Transduction in Multistage Carcinogenesis

carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.;

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Protein-Protein Interactions in Human Disease, Part B

Protein-Protein Interactions in Human Disease, Volume 111, Part B, promotes further research and development in the protein interaction;

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Regucalcin

in vertebrates. Regucalcin plays a multifunctional role in cellular regulation, including an inhibitory role in protein kinases, protein phosphatases, NO;

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Calmodulin

The authors consider small and poorly-studied groups of plant calcium-dependent protein kinases that directly interact with calmodulin;

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Vibrational Spectroscopy in Protein Research

international leaders in the field, the book addresses basic principles of vibrational spectroscopy in protein research, instrumentation and;

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Computational Chemistry

The development of new drugs always was time consuming and costly. With the development in experimental methods, it was possible to scan;

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Protein Biosynthesis Interference in Disease

Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms;

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Mitogen-Activated Protein Kinases (MAPKs)

Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation opens with a summary of the present knowledge about MAPK;

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Receptor-like Kinases in Plants

of receptor kinases, their signaling pathways, and the ways in which these important signaling proteins are regulated.;

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Protein Degradation in Health and Disease

is regulated by protein degradation and how its deregulation can contribute to the development of cancer, how protein degradation is modified during;

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