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Kinase Inhibitor Drugs

Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the;

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A Closer Look at Kinase Inhibition

A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms;

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Small Molecules in Hematology

small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor;

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Small Molecules in Hematology

small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor;

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The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

This issue of Hematology/Oncology Clinics will focus on The Treatment of Myeloid Malignancies with Kinase Inhibitors. Articles will focus;

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New Developments in Proteomics Research

This book presents new developments in proteomics research. Topics discussed include the serine proteinase inhibitor Z Alpha-1 antitrypsin;

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Kinomics

inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result;

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Novel Anticancer Drug Protocols

growth factor receptor tyrosine kinase for the treatment of metastatic breast cancer; and Gleevec, a small molecule bcr-abl kinase inhibitor for;

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Next Generation Kinase Inhibitors

clinically beneficial small molecule protein kinase inhibitor, there are only a few examples where these drugs provide sustained and durable patient;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy;

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Iressa-A Boon to Colon Cancer

variably dependent on autocrine stimulation of EGFR. This book therefore, examines the effects of a selective EGFR tyrosine kinase inhibitor;

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New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

Topics in this issueinclude: Targeting IGF-1R; Tyrosine Kinase Inhibitors in Lung Cancer; Targeting mTOR; Targeting Hedgehog; Mitotic;

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Protein Kinase-mediated Decisions Between Life and Death

provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions;

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Targeting Protein Kinases for Cancer Therapy

kinase inhibitors,focusing mostly on small molecules but also alternative approacheslike therapeutic antibodies. Provides an important resource;

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Leukemias

future and explain the rationale for ongoing clinical trials. Topics include: * Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora;

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Novel Therapeutic Targets for Antiarrhythmic Drugs

the chapter -- including arrhythmia mechanisms, kinase inhibitors, calcium and potassium channel targets, and atrial selective drugs.;

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Kinase Drug Discovery

mechanisms of kinases inhibitors. Also covered is resistance to kinase inhibitors caused by amino acid mutations, case studies of kinase programs and;

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Cox-2 Inhibitor Research

COX-2 Inhibitors are newly developed drugs for inflammation that selectively block the COX-2 enzyme. Blocking this enzyme impedes the;

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Trends in Cox-2 Inhibitor Research

Cox-2 Inhibitors are newly developed drugs for inflammation that selectively block the Cox-2 enzyme. Blocking this enzyme impedes the;

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Resistance to Anti Cancer Therapeutics Targeting Receptor Tyrosine Kinases and D

-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways;

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The Organic Chemistry of Drug Design and Drug Action

epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib for transition state analogue;

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Adverse Events and Oncotargeted Kinase Inhibitors

Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase;

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HIV-1 Integrase

This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists;

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Antineoplastic Drugs

syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty;

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Target Discovery and Validation

. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and;

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Protein Kinase Inhibitors in Research and Medicine

. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad;

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Targeted Therapies in Cancer

, along with about eighty other promising compounds. These drugs are members of various therapy classes, including tyrosine kinase inhibitors;

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