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Glycogen Synthase Kinase 3 (Gsk-3) And Its Inhibitors

Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes;

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Proteinkinase Inhibitors

inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to;

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Advances in Cancer Research

of glycogen synthase kinase-3 in cancer, chronic immune activation and inflammation in the pathogenesis of AIDS and cancer, and molecular biology;

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Resistance to Tyrosine Kinase Inhibitors

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common;

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The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic;

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Protein Kinase Inhibitors in Research and Medicine

. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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Kinase Inhibitors

Protein and lipid kinases are often the master regulators of cell signaling in eukaryotic systems. The human genome codes for more than 500;

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A Closer Look at Kinase Inhibition

A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms;

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Leukemias

of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the;

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Kinase Inhibitor Drugs

Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the;

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Targeted Therapies in Cancer

century has seen the emergence of targeted therapy, resulting from the identification of molecular pathways in cells and their alterations;

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New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

Inhibitors; Topoisomerase I Inhibitors; and New Strategies and Drugs Inhibiting Folate Pathways.;

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Kinase Drug Discovery

Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13;

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Phosphoinositide 3-kinase Signalling Pathway

and mechanisms of phosphoinositide 3-kinase (PI3Ks) signalling of all classes, with focus on the cellular context of PI3K activity, including;

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Targeting Protein Kinases for Cancer Therapy

This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase;

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Kinase Screening and Profiling

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug;

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Small Molecules in Oncology

covers a wide range of small molecules, including tyrosine kinase inhibitors, mTOR, MEK, PARP, and multikinase inhibitors, as well as cell cycle;

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Small Molecules in Oncology

covers a wide range of small molecules, including tyrosine kinase inhibitors, mTOR, MEK, PARP, and multikinase inhibitors, as well as cell cycle;

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Anti-Inflammatory Drug Discovery

, sphingolipids and others, to summarize its background biology and detail new insights, major advances and issues related to bringing new anti;

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Infections Related to Biologics An Issue of Infectious Disease Clinics of North America

In collaboration with Consulting Editor Dr. Helen Boucher, Drs. Aruna Subramanian and Dora Yuk-Wai Ho have created an extremely timely and;

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Adverse Events and Oncotargeted Kinase Inhibitors

Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase;

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Novel Therapeutic Targets for Antiarrhythmic Drugs

This book provides a comprehensive overview of several promising novel drug targets and approaches against arrhythmias, with particular;

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An Introduction to Cancer Therapy

This compilation attempts to provide readers with brief and concise information on different types of cancer, their origins, and available;

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Protein Kinases in Drug Discovery

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by;

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Small Molecules in Hematology

enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure;

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