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Physiologically Based Pharmacokinetic (PBPK) Model ing and Simulations

for improving drug discovery and development. This fully updated new edition covers key developments in the field of PBPK modelling and;

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Biomarkers in Clinical Drug Development

Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference;

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Pharmacokinetics in Drug Discovery and Development

approaches, Pharmacokinetics in Drug Discovery and Development serves as a resource for professionals throughout this field.;

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Basic Pharmacokinetics

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It;

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Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations

process of drug discovery and development. With end-of-chapter glossaries, extensive bibliographic references, and an emphasis on practical;

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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the;

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Lead Optimization for Medicinal Chemists

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a;

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Basic Clinical Pharmacokinetics

text provides an introduction to the principles of monitoring drug therapy for those involved in the interpretation of drug levels in a patient;

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Clinical Pharmacokinetics

. Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles;

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Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition

how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve themHelps you critically evaluate;

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Principles of Clinical Pharmacology

drug become obsolete as it is replaced by newer agents. Principles of Clinical Pharmacology focuses on the fundamentals that underlie;

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Applications of Pharmacokinetic Principles in Drug Development

This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development;

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Physiologically Based Pharmacokinetic (Pbpk) Modeling: Methods and Applications in Toxicology and Risk Assessment

principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic;

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Transporters in Drug Discovery and Development

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide;

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Drug Delivery Approaches - Perspectives from Pharmacokinetics and Pharmacodynamics

in development An examination of virtual experiment methods for integrating pharmacokinetic, pharmacodynamic, and drug delivery mechanisms Alternative;

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Principles of CNS Drug Development

. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety;

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Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics

drug applications. Key updates reflect advances in PK/PD as related to clinical decision-making and drug research and development. An;

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Clinical Pharmacokinetics

principles who will use the material to initiate dosing of the drugs covered in the various chapters and for monitoring the outcome of patients given;

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Pharmacokinetic Profiling in Drug Research

screened for 'drugability', i.e., for 'drug-like' properties such as good pharmacokinetic (PK) behavior. Pharmacokinetic profiling of bioactive;

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Pharmacokinetic Challenges in Drug Discovery

drug discovery process. One of the biggest challenges is the pharmacokinetic (PK) optimisation of drug candidates tailored and predicted to;

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Monte Carlo Simulation for the Pharmaceutical Industry

in drug development. It not only deals with the principles and methods of Monte Carlo simulation, but also the applications in drug development;

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Monte Carlo Simulation for the Pharmaceutical Industry

in drug development. It not only deals with the principles and methods of Monte Carlo simulation, but also the applications in drug development;

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Strategies to Modify the Drug Release from Pharmaceutical Systems

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug;

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Enzyme Inhibition in Drug Discovery and Development

This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both;

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Profiles of Drug Substances, Excipients and Related Methodology

: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic;

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Preclinical Drug Development

Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from;

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Profiles of Drug Substances, Excipients and Related Methodology

metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and;

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