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The Glutamate Synapse as a Therapeutic Target

targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization;

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Ionotropic Glutamate Receptors in the CNS

criteria for accept- ing a molecule as a chemical transmitter appear to be fulfilled at several synapses: Glutamate mimics the action of the;

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Synapse Therapeutic Learning Theory Stress Cognition Chronic pain Neuromuscular rehabilitation

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Glutamate

of acute brain insults; the physiology of glutamate receptors in schizophrenia; how glutamate works as a neurotransmitter and the role;

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Beginning Azure Synapse Analytics

Get started with Azure Synapse Analytics, Microsoft's modern data analytics platform. This book covers core components such as Synapse SQL;

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Kainic Acid

Kainic acid is a naturally occurring amino acid that is isolated from red algae and is known to cause amnesic shellfish poisoning via the;

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Glutamate and Addiction

In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems;

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The Immune Synapse

This volume provides all the essential protocols that are currently used to study the immune synapse. Chapters in The Immune Synapse;

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The Synapse

associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and;

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Metabotropic Glutamate Receptors

As the most abundant excitatory neurotransmitter in the brain, glutamate plays an important role in numerous aspects of normal and;

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Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and;

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The Synapse

The synapse not only provides a bridge from one nerve cell to the next; its function can be modified by experience, making it important for;

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Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

compounds at a certain target for their bioactivity, and second the evaluation of computer aided methods for the identification of virtual hits to;

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Amino Acid Fermentation

of academic research and industrial development. In 1908, the Japanese researcher Kikunae Ikeda discovered glutamate as an Umami substance. Then a new;

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Amino Acid Fermentation

soybean in the early days, a new production method was subsequently invented - fermentation - in which glutamate is produced from sugars such as;

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Dopamine - Glutamate Interactions in the Basal Ganglia

and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia are presented against a historical perspective;

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Dopamine - Glutamate Interactions in the Basal Ganglia

and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia are presented against a historical perspective;

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Modulators of Glutamatergic Signaling as Potential Treatments of Neuropsychiatric Disorders

in neurodevelopmental disorders such as autism. In addition to the above, recent discoveries that several novel therapeutic agents like riluzole, memantine;

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Synapse Development and Maturation

information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the;

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Glutamate Receptors

techniques and fields of study. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their;

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Emerging Therapeutic Ultrasound

, ultrasound assisted target drug and gene delivery, as well as transdermal drug delivery are discussed.The book will be a useful reference source for;

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Imaging AMPA-Type Receptors in Hippocampal Neurons

-type glutamate receptors at the synapse controls the strength of excitatory transmission and their number can be modulated. There is however a;

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Astrocytes and Epilepsy

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain;

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Inflammation and Epilepsy

therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure;

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Advances in Immunology

chapters on Eosinophil Development, Disease Involvement, and Therapeutic Suppression, Immunoglobulin A responses to the microbiota, Unexpected;

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Protein Degradation with New Chemical Modalities

Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a;

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Metabotropic Glutamate Receptors

Metabotropic Glutamate Receptors: Classification, Structure and Roles in Disease focuses on Glutamate (Glu), a neurotransmitter;

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