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Kainic Acid

postsynaptic effects through ionotropic and metabotropic receptors. Of the ionotropic glutamate receptors (GluRs), kainic acid has a high affinity for;

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Ionotropic Glutamate Receptors in the CNS

It is now widely accepted that glutamate is the major excitatory neurotrans- mitter in the mammalian central nervous system. The main;

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Allosteric Receptor Modulation in Drug Targeting

, ionotropic and metabotropic receptors for glutamate, muscarinic receptors and alpha 2 adrenoceptors to provide a firm foundation to the subject.;

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Ionotropic Glutamate Receptor Technologies

laboratory.Concise and easy-to-use, Ionotropic Glutamate Receptor Technologies aims to facilitate the implementation of specific methods to iGluR;

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G Protein-Coupled Receptors

, specifically -adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune;

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Metabotropic Glutamate Receptors

/neuromodulator the most widely present in neurons of excitatory pathways, both in the central and peripheral nervous system. The authors present and;

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Metabotropic Glutamate Receptors

As the most abundant excitatory neurotransmitter in the brain, glutamate plays an important role in numerous aspects of normal and;

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Glutamate

Glutamate is purported to be the most important transmitter for normal brain function. Nearly all excitatory neurons in the central nervous;

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Excitotoxicity

or ototoxicity) and in neurodegenerative diseases of the central nervous system (CNS) such as multiple sclerosis, Alzheimer's disease;

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Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers;

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Amino Acid Receptor Research

Amino acid receptors and cell surface proteins that bind amino acids and trigger changes which influence the behaviour of cells. Glutamate;

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Glutamate and Addiction

In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems;

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Glutamate Receptors

techniques and fields of study. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their;

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Glutathione In The Nervous System

of the antoxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic receptor function, and neuroprotection against;

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Adenosine Receptors in Neurodegenerative Diseases

the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include;

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Sigma Receptors

This is the 12th in the Neuroscience Perspectives Series. The existence of sigma receptors in the central nervous system has only;

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mGLU Receptors

Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes;

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Corticotropin-Releasing Factor

(CRF) as a neurotransmitter in the mammalian central nervous system (CNS). It includes descriptions of the anatomy of CRF and its receptors;

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Cytokines and the Brain

from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines;

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Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

Group I metabotropic glutamate receptors (mGluRs) play an important role in the treatment of numerous neurodegenerative, cognitive and;

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Imaging AMPA-Type Receptors in Hippocampal Neurons

Synaptic plasticity is the ability of the connections between nerve cells, called synapses, to change in strength. The presence of the AMPA;

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Pharmacology of 5-HT6 receptors, Part II

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains;

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Peptide Receptors, Part I

expression and pharmacology in the mammalian central nervous system. The functional role of neuropeptides and their receptors in the CNS has;

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The Glutamate Synapse as a Therapeutic Target

This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the;

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Dopamine in the CNS I

, neurochemistry, molecular biology and behavioural pharmacology of dopamine in the CNS. - The first volume deals with the history of dopamine, the anatomy;

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Sympathetic Nervous System Research Developments

within the central nervous system (CNS). Sympathetic neurons of the spinal cord (which is part of the CNS) communicate with peripheral;

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Reviews of Physiology, Biochemistry and Pharmacology 147

Ligand-gated ion channels mediate fast synaptic transmission in the central nervous s- tem (CNS) and at ganglionic and neuromuscular;

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