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Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

Group I metabotropic glutamate receptors (mGluRs) play an important role in the treatment of numerous neurodegenerative, cognitive and;

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Ligand Binding in the Transmembrane Region

Ligand Binding in the Transmembrane Region is een boek van Tobias Noeske;

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Metabotropic Glutamate Receptors

manipulation may strategically silence pain. In the concluding chapter, the authors reviewed the roles of Metabotropic Glutamate Receptors (mGluRs) and;

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Metabotropic Glutamate Receptors

pathological brain function. This book provides an overview of the role of metabotropic glutamate receptors (mGluRs) in basic brain functioning, such;

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G Protein-Coupled Receptors

signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay;

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Kainic Acid

postsynaptic effects through ionotropic and metabotropic receptors. Of the ionotropic glutamate receptors (GluRs), kainic acid has a high affinity for;

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Allosteric Receptor Modulation in Drug Targeting

, ionotropic and metabotropic receptors for glutamate, muscarinic receptors and alpha 2 adrenoceptors to provide a firm foundation to the subject.;

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mGLU Receptors

Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes;

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Vitamin Receptors

vitamin ligand to a protein and its sequela. The various groups of vitamin-binding proteins are particularly significant as they relate to the;

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Ionotropic Glutamate Receptors in the CNS

It is now widely accepted that glutamate is the major excitatory neurotrans- mitter in the mammalian central nervous system. The main;

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G Protein-Coupled Receptors, Part B

of Arrestin Binding to Muscarinic Receptors, Luciferase Reporter Assay for Unlocking Ligand-mediated Signaling of GPCRs, Assays to Measure GPCR;

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Reversible Ligand Binding

Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand;

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Affinity And Efficacy: The Components Of Drug-receptor Interactions

agonism, allosteric agonists and modulators, agonist bias, modulation of pathway selectivity, and the estimation of ligand affinity for active and;

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Glutamate

Glutamate is purported to be the most important transmitter for normal brain function. Nearly all excitatory neurons in the central nervous;

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Vitamin Receptors

takes a fresh approach to vitamin-binding proteins, with emphasis on the nature of the binding of the vitamin ligand to a protein and its;

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Nuclear Receptors in Development and Disease

release cover the Evolution of Nuclear Receptors and Ligand Signaling: Towards a Soft Key-Lock Model?, The Function and Evolution of Nuclear;

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Ligand-Receptor Energetics

of the treatment of multiple equilibria in successive steps of the binding of ligands to receptors. It also describes the calculations and;

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Glutamate and Addiction

In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems;

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Amino Acid Receptor Research

Amino acid receptors and cell surface proteins that bind amino acids and trigger changes which influence the behaviour of cells. Glutamate;

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Receptors

Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and;

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Quantitative Characterization of Ligand Binding

The book fills the void between rigorous theoretical discussions of ligand binding for physical chemists (often beyond the needs of bench;

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Signaling By Receptor Tyrosine Kinases

. Ligand binding stimulates the tyrosine kinase activity of the receptors, leading to recruitment of enzymes and adapter proteins that activate;

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Intercellular and Intracellular Communication

The complementary binding of a ligand and receptor is the basic language of intercellular communication and this book takes a broad look at;

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Glutamate Receptors

techniques and fields of study. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their;

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Virus Receptors

instances receptors are undefined entities, whose molecular details remain to be established. On the other hand the ligand, which recognizes the;

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Chemokines

disulfide bridges. Binding of chemokines to specific G protein-coupled receptors followed by downstream signaling defines their biological function;

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Nuclear Receptors

cancer; the effects of nitric oxide on nuclear receptors as a tool for studying gene regulation; vitamin K as a ligand of steroid and xenobiotic;

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