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Ligand-Receptor Energetics

are unaware of the origins of the fundamental concepts and theoretical constructs in ligand-receptor energetics may fail to recognize the;

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Affinity And Efficacy: The Components Of Drug-receptor Interactions

of receptors, and responses downstream from receptor activation. More light is thrown on ligand-gated ion channels and G protein-coupled receptors;

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Receptors

phenomena involving receptorligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions;

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Signaling By Receptor Tyrosine Kinases

. Ligand binding stimulates the tyrosine kinase activity of the receptors, leading to recruitment of enzymes and adapter proteins that activate;

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Central Functions of the Ghrelin Receptor

The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been;

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Computational Medicinal Chemistry for Drug Discovery

Chemistry for Drug Discovery surveys molecular structure computation, intermolecular behavior, ligand-receptor interaction, and modeling responding;

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Iressa-A Boon to Colon Cancer

The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon cancer cell lines are;

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Nuclear Receptors

cancer; the effects of nitric oxide on nuclear receptors as a tool for studying gene regulation; vitamin K as a ligand of steroid and xenobiotic;

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Virus Receptors

instances receptors are undefined entities, whose molecular details remain to be established. On the other hand the ligand, which recognizes the;

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Advances in Medicinal Chemistry

motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal;

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TAM Receptors in Health and Disease

family receptors and their ligands: Role in thrombosis, TAM receptors and its ligand mediated activation: Role in Atherosclerosis, Post;

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Aldosterone

Receptor, Regulation of Aldosterone Secretion, Leptin and Aldosterone, Cell- and Ligand-Specific Interactions in Mineralocorticoid Receptor;

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Chemokines

chemokine ligand-receptor interactions can also modulate cellular activation, survival, and proliferation, among other functions in homeostatic and;

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Receptor Phosphorylation

useful to all workers and students in the area of receptor-ligand interactions.;

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Textbook of Receptor Pharmacology

of receptor structure Quantitative functional studies of agonists and antagonists Ligand binding Signal transduction at the cell membrane;

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Textbook of Receptor Pharmacology

investigation of receptor structure Quantitative functional studies of agonists and antagonists Ligand binding Signal transduction;

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Regulation Of G Protein Coupled Receptor Function And Expression

, arrestins) in modulating receptor function; and the methods used to measure receptor trafficking (ligand binding, immunofluoresence) and expression;

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Receptor - Based Drug Design

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference;

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Receptor - Based Drug Design

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference;

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Fas Ligand Reverse Signaling

Binding of Fas Ligand (FasL) to the Fas receptor triggers apoptosis of the receptor-bearing cell, which plays a pivotal role for;

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The Histamine H3 Receptor

In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become;

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Receptor Localization

, ranging from genes and ligands to in vito receptors in individuals; and to numerous receptor subtypes, such as nicotine, muscarine, tackykinins;

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Immune Receptors

localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze;

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Textbook of Receptor Pharmacology

The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the;

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Vasopressin

and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic;

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Peroxisome Proliferator-Activated Receptors

differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances;

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Functional Selectivity of G Protein-Coupled Receptor Ligands

Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways;

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