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various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.
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use of these carriers for gene therapy and to target brain tumors. This volume will be of interest to researchers working on drug discovery;
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strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the;
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failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations;
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failure of adequate brain drug targeting, and that this is an increasingly urgent problem as developments in genomics lead to new generations;
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-based strategies. Different chem-bioinformatic modeling strategies that can be applied for design of multi-target drugs as well as important;
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This volume provides a guide on nanoformulations and other drug delivery approaches for both academic and industry scientists. The chapters;
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for clinical testing. It provides a thorough treatment of drug target discovery, validation, and development. The introductory chapters;
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This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on;
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This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on;
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Anaesthetic drugs with a rapid onset of action and a short half-live, such as the hypnotic propofol and the analgesic opioid remifentanil;
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development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The;
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development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The;
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Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and;
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for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug;
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target. A drug therefore binds to it and acts to activate or inhibit the function of the biomolecule thus conferring a therapeutic benefit to the;
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Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and;
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systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem;
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or in vitro procedures. In Silico Technologies in Drug Target Identification and Validation addresses the challenge of testing a growing;
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encompassing various means of achieving optimum drug reach to the target tissue, cell or the receptor.;
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biomolecular target, with which they interact and bind. The process in which the active drug and chemical substances are combined to produce a final;
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effects on other healthy tissues. Similarly, drug-specific delivery to some vital organs, such as the brain, lungs, heart and kidneys remains a;
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A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research;
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enzymes including transporters (mostly bad or undesirable enzyme inhibition) as well as the inhibition of drug target enzymes (mostly the;
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novel drug target. The book will open new vistas in exploitation of novel drug targets as a strategy to handle drug resistance problem;
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a small percent of the drug's target will be immune. These survivors can then lead to a new population, resistant to the action of this drug;
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Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest;
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