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or in vitro procedures. In Silico Technologies in Drug Target Identification and Validation addresses the challenge of testing a growing;
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Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and;
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identifying and characterizing vaccine targets for Brucella melitensis, in silico screening, and the identification of novel drug targets from the;
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application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical;
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application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical;
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optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design;
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Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry;
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The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols;
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step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and;
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for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights;
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. Technical topics discussed in the book include: * Drug discovery * Target identification and prioritization * Hypothesis driven multi-target drug;
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) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably;
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, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation;
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for clinical testing. It provides a thorough treatment of drug target discovery, validation, and development. The introductory chapters;
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automation in MS protein analysis * Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers;
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-of the art omics technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based;
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many marketed drugs are derived from phenotypic screens? From the most recent examples, what were the factors enabling target identification;
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In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized;
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field, with this new volume presenting interesting chapters on topics such as Target Identification and Validation, Cell Painting/High Content;
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-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based;
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of this process and this in many ways is analogous to the conventional target based drug designing concept. However, unlike cell based therapy it;
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of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed;
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Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data;
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and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches;
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phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design;
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This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target;
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technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section;
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