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Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic;

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Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their;

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Proteases as Targets for Therapy

evaluations of key viral, bacterial, fungal, and cellular proteases as potential future drug candidates.;

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Aspartic Acid Proteases as Therapeutic Targets

first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and;

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Antiviral Drug Strategies

of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases;

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Activation of Viruses by Host Proteases

in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and;

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Recollections of 45 Years in Research

to NCS, GBP called SMANCS. The author, having acquired knowledge of proteases and inhibitors, pioneered investigations of microbial proteases;

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Proteases

resources (databases, tools, visualization and data analysis) to provide a better understanding of proteases and their functions at the molecular;

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Role of Proteases in Cellular Dysfunction

It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play;

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Viral Polymerases

functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the;

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A Closer Look at Kinase Inhibition

of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases;

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Cancer-Leading Proteases

and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their;

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Infections Related to Biologics An Issue of Infectious Disease Clinics of North America

, hematologic malignancies, solid tumors, and other conditions; there is a lack of guidance in the literature on how to address their infectious risks;

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Selective Inhibitors of Viral Functions

modes of action, and their activities both in animal infections and clinical medicine.;

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Novel Therapies in Hepatitis C Virus, An Issue of Clinics in Liver Disease

include interferons, viral kinetics and anti-viral resistence, anti-fibrotics, immunotherapeutics, hepatoprotectants and caspace inhibitors, and;

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Proteases In Health And Disease

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will;

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Proteolytic Enzymes

in providing ideas and protocols for scientists either studying proteases or using proteases as a research tool.;

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Protease Inhibitors in AIDS Therapy

-key components of long-term viral suppression and immune restoration, and in secondary and tertiary regimens! Evaluating protease inhibitors;

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Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide;

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Serine Proteases

cascades. In this book, the authors discuss the maturation and stabilisation mechanisms of two hyperthermostable subtilisin-like serine proteases;

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Enzymes and Their Inhibitors: Drug Development

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise;

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Progress in Medicinal Chemistry

antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT;

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Proteases and Cancer

This volume explores the role of proteases in various catalytic classes and cellular processes associated with cancer. The chapters in this;

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Enzymes and Their Inhibitors: Drug Development

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise;

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Proteases in Tissue Remodelling of Lung and Heart

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease;

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Proteases in Tissue Remodelling of Lung and Heart

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under;

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Osteoarthritis, Inflammation and Degradation

from the best targeted pharmacological (anti-cytokines, inhibitors of signaling pathways, inhibitors of proteases, etc.) and non;

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Einde inhoud

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