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Cancer-Leading Proteases

Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets;

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Proteases and Cancer

This volume explores the role of proteases in various catalytic classes and cellular processes associated with cancer. The chapters in this;

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Role of Proteases in Cellular Dysfunction

of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to;

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Matrix Proteases in Health and Disease

cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing;

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Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their;

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Serine Proteases

cascades. In this book, the authors discuss the maturation and stabilisation mechanisms of two hyperthermostable subtilisin-like serine proteases;

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Proteases In Health And Disease

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will;

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Proteases

design of emerging technologies for production of novel proteases with enhanced specificity, stability and catalytic activity for a wide;

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Aspartic Acid Proteases as Therapeutic Targets

first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and;

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Proteases in Tissue Remodelling of Lung and Heart

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease;

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Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic;

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Proteases in Tissue Remodelling of Lung and Heart

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under;

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Human Stefins & Cystatins

proteases (cathepsins) inhibition. The chapters start at the level of genes, go on with protein structure and function (proposal of alternative;

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The Cancer Degradome

functionality, homeostasis, and fate at the levels of the cell and the entire organism. For the cancer cell, intracellular prote- ysis carried out by;

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Cysteine Proteases of Pathogenic Organisms

Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host;

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Cysteine Proteases of Pathogenic Organisms

Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host;

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Co- and Posttranslational Proteolysis of Proteins

mature protein to occur. The discussion of these various proteases is rarely undertaken in one volume and will serve as a great resource for;

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Activation of Viruses by Host Proteases

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized;

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Molecular & Structural Biology of New Lipases & Proteases

fields of molecular biology, structural biology, and crystallography for the two very important industrial enzymes: proteases and lipases;

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Extracellular Targeting of Cell Signaling in Cancer

International experts present innovative therapeutic strategies to treat cancer patients and prevent disease progression Extracellular;

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Biology of Serpins

Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The;

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Heparanase

activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement;

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Proteases in Health and Disease

Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion;

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A Closer Look at Proteolysis

authors of the eighth chapter consider the possibilities for the production of purification of Bacillus proteases and their application in various;

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Interferons

of interferons, Type I interferons are potent mediators of the innate immune response against viruses and cancer. Type II interferons, mainly IFN-y;

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Proteases as Targets for Therapy

therapeutics. Proteases control a large array of physiological reactions, and are involved in a variety of pathological processes for which effective;

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Proteases New Perspectives

This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological;

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Einde inhoud

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