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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the;
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detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a;
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sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost;
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new bioinformatics methods for drug discovery and environmental toxicology. This publication is an indispensable tool for postgraduates;
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chemists covers all the latest developments in the field of predictive toxicology and its applications in safety assessment. With a keen emphasis;
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experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances;
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physical chemistry, cheminformatics, biological sciences, predictive toxicology and safety and hazard assessment.;
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REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk;
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Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug;
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improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. Discusses the basics, drug delivery strategies;
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toxicology. Experts will discuss common drugs in analgesia, toxicology techniques, errors and interferences in toxicology testing, toxicology;
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The use of over-the-counter (OTC), prescription, and illicit drugs is increasing in the U.S. population. The National Transportation Safety;
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-based drug targeting, chemical mixture assessments, and environmental modeling Features coverage about consumer product safety assessment and;
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pharmaceuticals enter the market. In this comprehensive discussion of predictive toxicology and its applications, leading experts express their views on;
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A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete;
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Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a;
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includes new chapters on:* vaccine safety surveillance* managing drug safety issues with marketed products* operational aspects of drug safety;
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and chemicals, and in drug development. Thus, there is a growing need for an Illustrated Dictionary of Toxicology Pathology and Safety Science;
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Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and;
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Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically;
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, chemistry, drug discovery, predictive toxicology, systems biology, chemoinformatics, and bioinformatics Revised 2015 edition includes a new;
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. Before a drug substance can be tested in man, a set of toxicology studies must be carried out in animals and in vitro to ensure, as far as;
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their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology;
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areas of physics, chemistry, drug discovery, predictive toxicology, systems biology, chemoinformatics, and bioinformatics About half;
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The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be;
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target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose;
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-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro;
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