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Drug Discovery Toxicology

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the;

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Evaluation of Drug Candidates for Preclinical Development

Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes;

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Predictive Toxicology in Drug Safety

effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each;

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Zebrafish

well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the;

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Poisonous Plants and Phytochemicals in Drug Discovery

Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their;

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Antibody-Drug Conjugates

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers;

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Green Chemistry in Drug Discovery

This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a;

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Green Chemistry Strategies for Drug Discovery

, covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case;

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Oral Formulation Roadmap from Early Drug Discovery to Development

Covers regulatory filing, drug metabolism and physical and chemical properties, toxicology formulation, biopharmaceutics classification system;

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Lysosomes: Biology, Diseases, and Therapeutics

biochemistry to illustrate the potential of lysosomes in drug discovery and development. Explores basic principles and properties of lysosomes that;

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Toxicology and Drug Testing, An Issue of Clinics in Laboratory Medicine

toxicology. Experts will discuss common drugs in analgesia, toxicology techniques, errors and interferences in toxicology testing, toxicology;

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Computational Systems Pharmacology and Toxicology

both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological;

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Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a;

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Aminoglycoside Antibiotics

explore their tremendous potential for drug discovery and rational drug design. With chapters written by one or more leading experts in their;

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Computational and Structural Approaches to Drug Discovery

Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to;

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A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete;

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Drug Design Strategies

methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the;

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Karch's Drug Abuse Handbook

their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology;

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Multi Target Drug Design Using Chem Bioinformatic Approaches

This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure;

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Development of Vaccines

, challenges and solutions for progressing a biologic drug formulation from its early stage of discovery into its final clinical testing. A section;

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Prodrugs and Targeted Delivery

employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.;

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Cytochrome P450

are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels;

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Drug Discovery and Development

the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for;

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Advances in Mathematical Chemistry and Applications: Volume 1

, chemistry, drug discovery, predictive toxicology, systems biology, chemoinformatics, and bioinformatics Revised 2015 edition includes a new;

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Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has;

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Antisense-Based Drugs and Therapeutics

ALS. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide from the safety assessment to;

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Pharmaceutical Toxicology in Practice

central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands;

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