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Phosphodiesterases and Their Inhibitors

(PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE;

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Cyclic Nucleotide Phosphodiesterases in Health and Disease

therapeutically important area of medical research. Cyclic Nucleotide Phosphodiesterases in Health and Disease provides an integrated volume covering;

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Phosphodiesterases as Drug Targets

Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity;

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Phosphodiesterases CNS Functions and Diseases

and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis;

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CyclicNucleotide Phosphodiesterases in the Central Nervous System

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A;

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Enzymes and Their Inhibitors: Drug Development

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise;

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Enzymes and Their Inhibitors: Drug Development

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise;

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Pharmaceutical Biocatalysis

with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal;

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Corrosion Inhibitors in the Oil and Gas Industry

encountered and their control methods, environmental factors affecting inhibition, material selection strategies, and economic aspects of corrosion;

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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors

inhibitors and their clinical applications, as well as future prospects for their use. Up-to-date summary of biochemistry and pharmacology;

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Third Generation EGFR Inhibitors

> Provides a structural correlation of third and fourth generation EGFR inhibitors, reviewing both their design strategies and typical;

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Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic;

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Kinase Inhibitors

of these enzymes and their misregulation has been shown to be involved in the onset and progression of many diseases including cancer and;

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Kinase Inhibitors

of these enzymes and their misregulation has been shown to be involved in the onset and progression of many diseases including cancer and;

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Targeted Therapies in Cancer

century has seen the emergence of targeted therapy, resulting from the identification of molecular pathways in cells and their alterations;

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Alpha-glucosidase Inhibitors

side effects. Beginning with a discussion of the huge potential of a -glucosidase inhibitor leads and adaptations, and highlighting their;

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Antiviral Agents

protease inhibitors five have been marketed during 1995-1999. They are saquinavir, ritonavir, indinavir, nelfinavir and ampre- navir. Their;

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Protease Inhibitors as Cancer Chemopreventive Agents

development in a number of ways, including suppression of oxygen radicals, oncogenes, and metastases. Epidemiologic evidence supports their prevention;

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Comparative Pathophysiology and Toxicology of Cyclooxygenases

The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases;

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Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy

classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity.. Lastly, it discusses and;

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Therapeutic Targets

, phosphodiesterases, and potassium channels. Because different diseases can require their own targeting strategies, the book has chapters on the strategies;

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Theory and Applications of Green Corrosion Inhibitors

The book presents theoretical insights, characterization tools and mechanisms of green corrosion inhibitors. Keywords: Biocorrosion;

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Evaluation of Enzyme Inhibitors in Drug Discovery

With enzymes being the most valued and common of drug targets, an understanding of their interactions with inhibitors is critical to;

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Phosphodiesterase Inhibitors

of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

sensitizing agents to their research in clinical practice and in trials. Summarizes the sensitizing role of some tyrosine kinase;

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Proteinkinase Inhibitors

This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a;

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Ionic Liquids in Flow Assurance

This book focuses on the application of ionic liquids in flow assurance in the oil and gas industry. It discusses their physiochemical;

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