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Nmr in Ligand Screening

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Applied Biophysics for Drug Discovery

not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: Design considerations in biophysical;

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Biological NMR Part B

Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new;

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Biological NMR Part A

Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new;

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High-Resolution NMR Techniques in Organic Chemistry

High-Resolution NMR Techniques in Organic Chemistry, Third Edition describes the most important NMR spectroscopy techniques for the;

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Fragment-Based Drug Discovery

project library building and production NMR in fragment screening and follow up application of protein-ligand NOE matching to the rapid evaluation;

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Label-Free Technologies For Drug Discovery

the power and limitations of label-free in all areas of drug discovery. Label-free technologies discussed include SPR, NMR, high-throughput;

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Protein-Ligand Interactions

The two Practical Approach volumes on protein-ligand interaction do not comprise a comprehensive compilation of all the methods that can be;

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Virtual Screening in Drug Discovery

Virtual screening can reduce costs and increase hit rates for lead discovery by eliminating the need for robotics, reagent acquisition or;

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Virtual Screening in Drug Discovery

Virtual screening can reduce costs and increase hit rates for lead discovery by eliminating the need for robotics, reagent acquisition or;

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Annual Reports on NMR Spectroscopy

of Hyperpolarus Long-Lived States in Drug Screening, and Characterization of Mixed Network Phosphate Classes by 1D and 2D NMR Techniques, amongst other;

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Fragment-based Approaches in Drug Discovery

ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery;

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Protein-Ligand Interactions

for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison;

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Nmr and Chemistry

Keeping mathematics to a minimum, this book introduces nuclear properties, nuclear screening, chemical shift, spin-spin coupling, and;

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Structure-Based Drug Discovery

throughput structure determination, probing protein-ligand interactions by NMR spectroscopy, virtual screening and fragment-based drug discovery. The;

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Mass Spectrometry in Medicinal Chemistry: Applications in Drug Discovery

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug;

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Biomolecular Structure and Dynamics

simulations, X-ray crystallography and NMR of biomolecules, the structure of proteins and its prediction, time resolved Fourier transform IR;

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Methods for fragments screening using Surface Plasmon Resonance

This volume describes methods and protocols for the fragment-based screening of proteins using Surface Plasmon Resonance (SPR). The initial;

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Artificial Riboswitches

Artificial riboswitches and other ligand-responsive gene regulators make it possible to switch protein synthesis ON or OFF with arbitrary;

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Iressa-A Boon to Colon Cancer

, Gefitinib ('Iressa', ZD1839), on proliferation and survival of colon cancer cell lines whose autonomous proliferation is either EGFR ligand;

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Ligand Design in Metal Chemistry

The design of ancillary ligands used to modify the structural and reactivity properties of metal complexes has evolved into a rapidly;

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Physico-chemical Studies on the Complexes

investigation, proton-ligand stability constant, pKH, of azosulfonamide rhodanine compounds will be determined potentiometrically in 20% (v/v) DMF-water;

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Computational Approaches to Nuclear Receptors

Nuclear receptors (NR) are ligand-induced activated transcription factors that are involved in numerous biological processes. Since the;

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Reversible Ligand Binding

Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand;

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Drug Design

Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and;

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Computational Chemogenomics

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target;

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Ligand Binding in the Transmembrane Region

Ligand Binding in the Transmembrane Region is een boek van Tobias Noeske;

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