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Fragment-Based Drug Discovery

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules;

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Fragment-Based Drug Discovery

Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics;

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Fragment-Based Drug Discovery

From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand;

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Fragment-based Approaches in Drug Discovery

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information;

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Dynamic Combinatorial Chemistry

, and analytical chemistry challenges. A single-source reference about modern methods in fragment-based drug discovery and DCC methods and;

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Structure-Based Drug Discovery

throughput structure determination, probing protein-ligand interactions by NMR spectroscopy, virtual screening and fragment-based drug discovery. The;

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Rational Drug Design

screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based;

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Applied Biophysics for Drug Discovery

in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment;

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Current Progress in Drug Discovery and Development

. Other methods of drug discovery include de novo drug design, fragment-based lead discovery and protein-directed dynamic combinatorial chemistry;

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Structural Biology in Drug Discovery: Methods, Techniques, and Practices

With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches;

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A Handbook for DNA-Encoded Chemistry

-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying;

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Handbook of Assay Development in Drug Discovery

to the increasing use of multiwell assays for drug discovery. The Handbook of Assay Development in Drug Discovery is a reference that;

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Drug Design

covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, linear-scaling quantum;

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Modern Approaches in Drug Discovery

-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit;

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Platform Technologies in Drug Discovery and Validation

-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation;

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Basic Principles of Drug Discovery and Development

through high through-put screening, fragment-based drug design, and computational chemistry;

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Computational and Structural Approaches to Drug Discovery

Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to;

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Text Mining for Genomics-based Drug Discovery

Text Mining for Genomics-based Drug Discovery is een boek van Patrick Herron;

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A Pharmacology Primer

encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets;

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Protein Interactions as Targets in Drug Discovery

Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and;

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Chemical Library Design

Chemical library technologies have brought about dramatic changes in the drug discovery process, and, though still evolving, they have;

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Biomolecular Simulations in StructureBased Drug Discovery

A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery;

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Achieving Proof of Concept in Drug Discovery and Development

One of the major shortcomings of the current drug discovery and development process is the inability to bridge the gap between early stage;

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Label-Free Technologies For Drug Discovery

beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery summarises the;

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Conference on Drug Design and Discovery Technologies

This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at;

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Drug Discovery And Development

From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug;

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A Pharmacology Primer

in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based;

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