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Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules;
Vergelijkbare producten zoals Fragment-Based Drug Discovery
From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand;
Vergelijkbare producten zoals Fragment-Based Drug Discovery
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information;
Vergelijkbare producten zoals Fragment-based Approaches in Drug Discovery
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics;
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, and analytical chemistry challenges. A single-source reference about modern methods in fragment-based drug discovery and DCC methods and;
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With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches;
Vergelijkbare producten zoals Structural Biology in Drug Discovery: Methods, Techniques, and Practices
-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit;
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Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules;
Vergelijkbare producten zoals Applied Biophysics for Drug Discovery
Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to;
Vergelijkbare producten zoals Computational and Structural Approaches to Drug Discovery
screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based;
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throughput structure determination, probing protein-ligand interactions by NMR spectroscopy, virtual screening and fragment-based drug discovery. The;
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covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, linear-scaling quantum;
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. Other methods of drug discovery include de novo drug design, fragment-based lead discovery and protein-directed dynamic combinatorial chemistry;
Vergelijkbare producten zoals Current Progress in Drug Discovery and Development
to the increasing use of multiwell assays for drug discovery. The Handbook of Assay Development in Drug Discovery is a reference that;
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-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying;
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There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols;
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methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the;
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has contributed significantly to the discovery of several marketed drugs and it is well known that in silico approaches are comparatively;
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-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation;
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the latest advances and technologies in diverse approaches to drug discovery, covering: Existing antivirals, including broadly effective anti;
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through high through-put screening, fragment-based drug design, and computational chemistry;
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hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action;
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encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets;
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current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through;
Vergelijkbare producten zoals Bioinformatics and Computational Biology in Drug Discovery and Development
the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from key targets and;
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current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through;
Vergelijkbare producten zoals Bioinformatics and Computational Biology in Drug Discovery and Development
effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each;
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