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Fragment-Based Drug Discovery

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules;

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Fragment-Based Drug Discovery

From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand;

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Fragment-based Approaches in Drug Discovery

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information;

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Fragment-Based Drug Discovery

Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics;

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Dynamic Combinatorial Chemistry

, and analytical chemistry challenges. A single-source reference about modern methods in fragment-based drug discovery and DCC methods and;

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Structural Biology in Drug Discovery: Methods, Techniques, and Practices

With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches;

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Modern Approaches in Drug Discovery

-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit;

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Applied Biophysics for Drug Discovery

Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules;

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Computational and Structural Approaches to Drug Discovery

Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to;

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Rational Drug Design

screening of chemical hits, rational lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based;

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Structure-Based Drug Discovery

throughput structure determination, probing protein-ligand interactions by NMR spectroscopy, virtual screening and fragment-based drug discovery. The;

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Drug Design

covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, linear-scaling quantum;

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Current Progress in Drug Discovery and Development

. Other methods of drug discovery include de novo drug design, fragment-based lead discovery and protein-directed dynamic combinatorial chemistry;

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Handbook of Assay Development in Drug Discovery

to the increasing use of multiwell assays for drug discovery. The Handbook of Assay Development in Drug Discovery is a reference that;

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A Handbook for DNA-Encoded Chemistry

-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying;

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Fragment Based Drug Design

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols;

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Drug Design Strategies

methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the;

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Masala or Medicine?

has contributed significantly to the discovery of several marketed drugs and it is well known that in silico approaches are comparatively;

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Platform Technologies in Drug Discovery and Validation

-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation;

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Combating The Threat Of Pandemic Influenza

the latest advances and technologies in diverse approaches to drug discovery, covering: Existing antivirals, including broadly effective anti;

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Basic Principles of Drug Discovery and Development

through high through-put screening, fragment-based drug design, and computational chemistry;

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Computational Chemogenomics

hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action;

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A Pharmacology Primer

encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets;

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Bioinformatics and Computational Biology in Drug Discovery and Development

current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through;

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Carbohydrates in Drug Design and Discovery

the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from key targets and;

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Bioinformatics and Computational Biology in Drug Discovery and Development

current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through;

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Predictive Toxicology in Drug Safety

effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each;

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