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Handbook of Mitochondrial Dysfunction

two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal;

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Mitochondrial DNA

methodologies for mitochondrial DNA analysis. of Mitochondrial DNA: Methods and Protocols describes protocols for detecting mutations in mitochondrial;

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Mitochondria in Health and Disease

It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles;

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Mitochondria in Health and Disease

It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles;

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Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases

This book describes the author's work on the development of sequence-specific DNA binders for the therapy of mitochondrial diseases. In the;

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Mitochondrial DNA and Diseases

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the;

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Understanding Mitochondrial Diseases

diseases are PCR and specific mutation analysis, southern blot and sequencing. Spindle therapy, embryonic mitochondrial transplant and protofection;

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Mitochondrial Diseases

of mitochondrial DNA, e.g. its in vivo conformational changes, and models of deletions and partition. Moreover, it discusses the involvement;

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Mitochondrial DNA, Mitochondria, Disease and Stem Cells

during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional;

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Mitochondrial DNA, Mitochondria, Disease and Stem Cells

during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional;

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Mitochondrial Medicine

, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role;

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Mitochondrial Oxidative Phosphorylation

subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a;

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The Charnoly Body

of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and;

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The Charnoly Body

of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and;

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Mitochondrial Diseases

Mitochondrial diseases comprise a clinically and genetically heterogeneous group of rare disorders that may affect virtually any system;

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Mitochondrial Disorders

of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely;

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Mitochondrial Disorders Biochemical and Molecular Analysis 837 Methods in Molecular Biology

of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely;

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Mitochondrial Neuropathies: Volume 145

Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role;

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Mitochondrial Dysfunction in Ageing and Diseases

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Mitochondrial Dysfunction in Aging and Diseases of Aging

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Mitochondrial Biology

With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely;

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DNA Repair, Genomic Instability and Cancer: Special Topic Issue

manuscripts and review articles in this special issue covers a wide range of topics on G-quadruplex ribosomal DNA, impaired mitochondrial DNA function;

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Mitochondrial Medicine

diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.;

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DNA Replication and Human Disease

generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to;

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Mitochondrial Case Studies

approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will;

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Mitochondrial Function in Lung Health and Disease

in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury;

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Bidirectional Gene Promoters

partner NPAT and MCM4, respectively. Surveillance of the human DNA database has revealed that the numbers of DNA repairmitochondrial function;

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