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Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases

This book describes the author's work on the development of sequence-specific DNA binders for the therapy of mitochondrial diseases. In the;

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Mitochondria in Health and Disease

with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number;

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Mitochondria in Health and Disease

with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number;

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Understanding Mitochondrial Diseases

in the mitochondrial DNA or in nuclear genes which code for mitochondrial components. Some of the conditions for which there exists evidence for;

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Handbook of Mitochondrial Dysfunction

focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through;

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Mitochondrial DNA

within the mitochondria, methods for analyzing mitochondrial DNA replication, mitochondrial DNA-encoded protein translation and mitochondrial DNA;

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Advances in DNA Sequence-Specific Agents

critical interactions. As our understanding of the genome and proteome expands, general developments in the field of DNA sequence specific;

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Mitochondrial Diseases

of mitochondrial DNA, e.g. its in vivo conformational changes, and models of deletions and partition. Moreover, it discusses the involvement;

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Mitochondrial Oxidative Phosphorylation

subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a;

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Mitochondrial DNA and Diseases

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the;

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The Charnoly Body

of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and;

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The Charnoly Body

of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and;

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Artificial Assemblies with Cooperative DNA Recognition

strategy for PIP design cannot apply to flexible DNA binding-for example, the DNA-binding mode of a transcription factor pair. In this book;

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Artificial Assemblies with Cooperative DNA Recognition

strategy for PIP design cannot apply to flexible DNA binding-for example, the DNA-binding mode of a transcription factor pair. In this book;

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Advances in DNA Sequence-Specific Agents

group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the;

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Mitochondrial Neuropathies: Volume 145

Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role;

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Mitochondrial Disease Genes Compendium

under way for over 250 mitochondrial diseases;

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Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably;

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Mitochondrial Medicine

, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role;

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Autologous And Cancer Stem Cell Gene Therapy

regenerative gene therapy and 2) of tackling most pathologies (including mitochondrial DNA diseases and ageing disorders) through stem cell;

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Mitochondrial Medicine

Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative;

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Mitochondrial DNA, Mitochondria, Disease and Stem Cells

during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional;

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Mitochondrial DNA, Mitochondria, Disease and Stem Cells

during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional;

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Gene Therapy for Diseases of the Lung

This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering;

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Mitochondrial Medicine

, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial;

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DNA Repair

The maintenance of DNA integrity and genome stability is essential for the viability of cells and the life of organisms. The genetic;

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Mitochondria and the Heart

organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an;

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