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manuscripts and review articles in this special issue covers a wide range of topics on G-quadruplex ribosomal DNA, impaired mitochondrial DNA function;
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Chromatin and DNA Repair in Cancer, Volume 364 in the International Review of Cell and Molecular Biology series reviews and details;
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damage and genomic instability. Abnormalities in these processes have been implicated in cancer and ageing. This book presents leading-edge;
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2015 was awarded for DNA repair (Paul Modrich, Aziz Sancar and Tomas Lindahl). Furthermore, genomic uracil has received wide interest among;
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in the fields of DNA damage repair and genomic stability and their implications in carcinogenesis, new approaches in cancer therapy, and cancer;
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regulated to avoid genomic instability, which can lead to diseases such as cancer, and how they are coordinated with other nuclear processes (e.g;
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DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference;
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adaptive function of sex in bacteria and eukaryotes; DNA repair as a therapeutic target in breast cancer; DNA repair in the nervous system;
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. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability;
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instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway;
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A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The;
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Many cancer biologists now believe that genomic instability not only initiates carcinogenesis, but also allows the tumour cell to become;
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repair, methods to quantify and analyze the properties of DNA double-strand breaks, profile replication, replication proteins strand-specifically;
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of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the;
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of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the;
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DNA repair is a rapidly advancing field in biology. DNA repair systems represent a major defense mechanism against environmental and;
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In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This;
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role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a;
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support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a;
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presenting interesting chapters on a variety of timely topics, including the Repair of replication-born DNA breaks by sister chromatid recombination;
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Genomic instability is a major threat to living organisms. To counteract the damaging effects posed by endogenous and environmental agents;
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This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now;
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DNA molecules undergo chemical reactions which may alter their structure and DNA repair is the process by which such damages are repaired;
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independently discovered in the laboratories of Paul Mandel, Osamu Hayaishi and Takashi Sugimura, all whom contribute to ADP-Ribosylation, DNA Repair;
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; Targeting DNA damage response and repair as a therapeutic strategy for ovarian cancer; Mechanisms of drug resistance in ovarian cancer; The status;
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focuses on DNA repair enzymes. Topics in this new release include chapters on the Optimization of Native and Formaldehyde iPOND Techniques for Use;
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This book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from;
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