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include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel;
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involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors;
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either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas;
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experts from academia and industry, G Protein-coupled Receptors: Molecular Pharmacology offers a unique view of academic and applied approaches;
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Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and;
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pharmacology. Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique;
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Quantitative Molecular Pharmacology and Informatics in Drug Discovery Michael Lutz, Section Head, Cheminformatics Group and Terry Kenakin;
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' extensive use of drug structures for teaching chemical and molecular pharmacology principles, and their emphasis on the relevance of these;
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with each other and cover general mechanisms, methodological approaches and cover selected important GPCR systems, the consequences for drug;
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With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular;
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of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the;
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of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the;
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the principles of pharmacology and pharmacokinetics, this volume alerts the reader to factors that affect drug action such as disease;
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, Emerging GPCR signaling pathways in cancer, and more. G protein-coupled receptors (GPCRs) constitute a large family of cell surface;
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purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling;
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This reference work gives a compete overview of the different stages of drug development using a translational approach. The book;
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Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug;
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of pharmacology, drugs and receptors, pharmacokinetics and drug interactions are all considered, along with the inclusion of the latest drug guidelines;
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This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and;
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rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these;
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G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new;
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in pharmacology and should be understood as such by all drug researchers whatever their background. When used as probes or medicines, stereoisomeric drugs;
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The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential;
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pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular;
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With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one;
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Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and;
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