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G ProteinCoupled Receptors as Drug Targets

With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an;

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G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis

cause monogenic obesity in humans. Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug;

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G Protein-Coupled Receptors in Drug Discovery

of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled;

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G Protein-Coupled Receptors in Drug Discovery

of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled;

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G Proteincoupled Receptors

of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors;

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Nuclear Receptors as Drug Targets

reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR;

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Receptor - Based Drug Design

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference;

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Receptor - Based Drug Design

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference;

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Novel Biosensors Using Intact Liposome Microarrays

industry as almost half of the 100 best-selling drugs on the market are targeted to a membrane receptor. More than 50% of current drug targets are;

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Ocular Transporters and Receptors

emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to;

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Advances in Agrochemicals: Ion Channels and G Protein-Coupled Receptors (GPCRs) as Targets for Pest Control Volume 2

targets, such as G-protein-coupled receptors (GPCRs) for screening, discovery, and development of novel agrochemicals. This book features;

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Histamine Receptors as Drug Targets

on practical, hands-on protocols from experts in the techniques. Authoritative and thorough, Histamine Receptors as Drug Targets seeks to aid;

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Orphan G Protein-Coupled Receptors and Novel Neuropeptides

Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel;

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Medicinal Chemistry for Practitioners

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful;

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Chemokine Receptors as Drug Targets

current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to;

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Progress in Medicinal Chemistry

The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as;

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G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors, with more than 800 members identified thus far in the;

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G Protein-Coupled Receptors

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances;

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G ProteinCoupled Receptors

G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for;

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Regulation Of G Protein Coupled Receptor Function And Expression

of receptor desensitization, and assessment of receptorG protein coupling); the role of regulatory proteins (receptor kinases and phosphatases;

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Allosteric Receptor Modulation in Drug Targeting

to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems-helping those new to;

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Trafficking of GPCRs

G protein-coupled receptors (GPCRs) constitutethelargest superfamily of cell surface receptors that regulate a variety of cell;

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Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential;

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Functional Selectivity of G Protein-Coupled Receptor Ligands

in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can;

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Affinity And Efficacy: The Components Of Drug-receptor Interactions

The interaction of a drug with a receptor generates a code of information having components of affinity and efficacy. How this information;

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GPCR Molecular Pharmacology and Drug Targeting

involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors;

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Neuropeptide Y and Drug Development

of research affected by NPY, such as food intake and energy homeostasis, cardiovascular regulation and G-protein-coupled receptors, as well as those;

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