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Nuclear Receptors as Drug Targets

reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR;

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Nuclear Receptors in Drug Metabolism

This book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with;

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Computational Approaches to Nuclear Receptors

simplifying this time-consuming and money-intensive research of lead compounds and, possibly, new drugs. Biological interactions such as those that;

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Ocular Transporters and Receptors

emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to;

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G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis

targets, with significant potential as new anti-obesity drugs Chapters are written by leading experts;

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Histamine Receptors as Drug Targets

on practical, hands-on protocols from experts in the techniques. Authoritative and thorough, Histamine Receptors as Drug Targets seeks to aid;

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Nuclear Receptors

as regulators in numerous essential biological functions. In this book, the authors present topical research in the study of nuclear;

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Nuclear Receptors in Development and Disease

Action During Development. The book's chapters provide a comprehensive set of reviews that cover such topics as nuclear;

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Medicinal Chemistry for Practitioners

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful;

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Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease

-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug;

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G Protein-Coupled Receptors in Drug Discovery

of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled;

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G Protein-Coupled Receptors in Drug Discovery

of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled;

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Chemokine Receptors as Drug Targets

current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to;

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Novel Biosensors Using Intact Liposome Microarrays

industry as almost half of the 100 best-selling drugs on the market are targeted to a membrane receptor. More than 50% of current drug targets are;

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Nuclear Receptors in Development

nuclear receptor subfamilies - such as TRs, PPARs, RARs, the orphan receptors COUP-TFs, RORs, and Ftz-F1 in embryonic and postnatal development;

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G ProteinCoupled Receptors as Drug Targets

with each other and cover general mechanisms, methodological approaches and cover selected important GPCR systems, the consequences for drug;

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Nuclear Receptors and Genetic Disease

Nuclear Receptors and Genetic Disease provides the first compilation of the role of nuclear hormones in health and disease and incorporates;

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Receptor - Based Drug Design

illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design. Explains the;

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Receptor - Based Drug Design

illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design. Explains the;

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Handbook of Assay Development in Drug Discovery

as non-class specific assay development for cell-based assays. It covers a wide range of target classes-including kinases, proteases, nuclear;

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Brucella Melitensis

in pathogenic bacteria and viruses,in general, and in B. militensis 16M in particular. Chapters identify putative genes as potential drug targets;

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Protein-Protein Interactions In Drug Discovery

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying;

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Metabotropic Glutamate Receptors

. Some novel therapeutical drug targets for controlling epilepsy and epileptogenesis are proposed.;

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Advances in Agrochemicals: Ion Channels and G Protein-Coupled Receptors (GPCRs) as Targets for Pest Control Volume 2

targets, such as G-protein-coupled receptors (GPCRs) for screening, discovery, and development of novel agrochemicals. This book features;

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Progress in Medicinal Chemistry

The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as;

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Molecular Pharmacology

and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters;

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Nuclear G-Protein Coupled Receptors

signaling systems is provided, as well as numerous chapters focusing on methods designed to understand signaling mediated by nuclear and other;

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