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This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and;
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Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development;
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epigenetic machinery, including the discovery and development of vorinostat, the first marketed epigenetic drug.;
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Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with;
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epigenetic biology and clinical application as epigenetic targets for drug discovery;
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"bench-to-bedside", discussing basic science, disease management, current debates, and next steps in epigenetic research and drug discovery
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Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number;
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Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development;
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uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics;
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With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches;
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examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well;
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pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic;
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studies from recent and on-going drug discovery projects for a variety of target classes, from kinases and phosphatases to targeting protein;
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of polyamine-based epigenetic modulators are detailed. Each chapter addresses a different aspect of polyamine drug discovery and all are written by;
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This book offers an integrated review of the most recent trends in natural products drug discovery and key lead candidates that are;
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role in preventive medicine and drug discoveryCovers the basic functionality of epigenetic mechanisms involved in early disease;
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pushing discovery forward and beyond the epigenetic realm. Discusses technologies that are critical for epigenetic research and;
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Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D;
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Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide;
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Polypharmacology can be the two-faced Janus in drug discovery and pharmacology: an adverse, off-target safety risk in some cases or a;
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epigenetic mechanisms underlying the formation and progression of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and;
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overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre;
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Drug discovery is a significant part of medicine, pharmacology and biotechnology, which is concerned with the discovery of new and improved;
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From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug;
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Providing a handy reference to synthetic methods and practical techniques, Heterocyclic Chemistry in Drug Discovery fuses heterocyclic;
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Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization;
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A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research;
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