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DNA-binding aromatic drug molecules

the cellular level. This review focuses on the biological role of direct intermolecular interaction of DNA-binding aromatic drug molecules;

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DNA Binding & DNA Extraction

. Topics discussed in this compilation include DNA binding to cationic polymers and its implications on gene therapy; metal based anticancer drug;

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Organic Photochemistry and Photophysics

photochemistry and photophysical behavior in aromatic molecules, thiocarbonyls, selected porphyrins, and metalloporphyrins. The book presents theories;

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Organic Photochemistry and Photophysics

photochemistry and photophysical behavior in aromatic molecules, thiocarbonyls, selected porphyrins, and metalloporphyrins. The book presents theories;

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DNA-targeting Molecules as Therapeutic Agents

examples of DNA-interactive molecules and technologies in development as therapeutic agents. DNA-binding metal complexes, peptide and polyamide-DNA;

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Thermodynamics and Kinetics of Drug Binding

, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It;

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Novel Enzyme / DNA Inorganic Materials

). These novel nanobiocomposite materials provide a simple method for the binding of DNA to negatively charged solids, and such approaches aid;

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Computer Aided Drug Design

known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins;

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Protein Interactions as Targets in Drug Discovery

Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and;

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Sequence-specific DNA Binding Agents

The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the;

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Templated DNA Nanotechnology

DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications;

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Chemosensors

Chemosensors?organic molecules designed to bind and sense small molecules or metal ions?function as molecular-level sensors that generate a;

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Ligand Binding in the Transmembrane Region of Metabotropic Glutamate Receptors

be screened on the pharmacological assays. Promising molecules were optimized regarding bioactivity and selectivity, their binding mode;

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Introduction to Macromolecular Binding Equilibria

Macromolecules in the body form noncovalent associations, such as DNA-protein or protein-protein complexes, that control and regulate;

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Introduction to Macromolecular Binding Equilibria

Macromolecules in the body form noncovalent associations, such as DNA-protein or protein-protein complexes, that control and regulate;

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Tetracyclines and Macromolecule

Tetracyclines are well known broad spectrum antibiotics, bind with macromolecules (serum albumin and DNA). The higher binding affinity;

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Solid-Phase Synthesis

of compounds for drug discovery and analyzes peptides, DNA, carbohydrates, conjugates of biomolecules, and small molecules.;

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Protein Interactions: Computational Methods, Analysis and Applications

This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular;

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Drug Design and Discovery

on large molecules, especially peptides and proteins, as well as DNA therapeutics. In Drug Design and Discovery: Methods and Protocols;

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The Quantum Theory of Atoms in Molecules: From Solid State to DNA and Drug Design

This book distills the knowledge gained from research into atoms in molecules over the last 10 years into a unique, handy reference;

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Innovations and Implementations of Computer Aided Drug Discovery Strategies in R

molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical;

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Artificial Assemblies with Cooperative DNA Recognition

DNA-binding pyrrole-imidazole polyamides (PIPs). PIPs represent the best-characterized class of small molecule DNA binders that can be;

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Artificial Assemblies with Cooperative DNA Recognition

DNA-binding pyrrole-imidazole polyamides (PIPs). PIPs represent the best-characterized class of small molecule DNA binders that can be;

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The Immunoglobins

describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis;

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Dynamic Combinatorial Chemistry

basic theory, approaches to binding in proteins and small molecules, molecular recognition, catalyst discovery, click chemistry, SAR by NMR;

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Advances in DNA Sequence-Specific Agents

interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter;

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Nanostructures and Nanoconstructions based on DNA

formed by DNA molecules and their complexes: (i) the hybridization approach and (ii) the liquid-crystalline approach The physicochemical;

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