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The Ubiquitin-Proteasome System and Disease

This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease. The editors and;

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The Ubiquitin-proteasome System

/dephosphorylation in the regulation of cellular activities. Understanding the ubiquitin-proteasome system and related mechanisms will provide new;

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Ubiquitin-proteasome Proteolytic System, The

system including circadian rhythms, axon guidance and acquisition of memory.This book tells the story of the ubiquitin system as we currently;

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Ubiquitin Family Modifiers and the Proteasome

The ubiquitin-proteasome system (UPS) and ubiquitin-related modifiers are not only involved in cellular protein quality control but also;

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Cell Biology of the Ubiquitin-Proteasome System

The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required;

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Ubiquitin-dependent Protein Degradation

proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway;

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Ubiquitin Proteasome System

Over the last decade, major advancements in our understanding of the ubiquitin-proteasome system (UPS) have occurred. This book focuses on;

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Ubiquitin Proteasome System in the Central Nervous System

The ubiquitin-proteasome field has experienced a breathtaking development from obscure origins in the late 1970s and early 1980s, through a;

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Ubiquitin and Ubiquitin-like Protein Modifiers

length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to;

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The Proteasomal System in Aging and Disease

-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure;

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Modulation of Protein Stability in Cancer Therapy

editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and;

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International Review of Cell and Molecular Biology

Self-Incompatibility and Self-Pollen Rejection, Regulation of Plant Immunity by the Proteasome, the Role of the Ubiquitin Proteasome System;

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Protein-Protein Interactions in Human Disease, Part A

, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics;

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Molecular and Translational Vascular Medicine

of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the;

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Molecular and Translational Vascular Medicine

of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the;

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Ubiquitin and the Biology of the Cell

sketched, and the importance of ubiquitin-dependent proteolysis as a regulatory mechanism gained general acceptance. The many strands of work that;

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Natural Products

chemopreventors; natural products as inhibitors of ubiquitin and ubiquitin-like protein-proteasome pathways; the biological activities of red propolis;

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Cell Cycle Control

of short-lived proteins, such as cyclins and CDKIs, and degradation of these proteins is mainly mediated by the ubiquitin-dependent proteasome;

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Progress in Cell Cycle Control Research

is driven by changes in the substrate specificity and subcellular localisation of cyclin-dependent kinases (Cdks), which in turn are modulated by a;

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Role of Proteases in Cellular Dysfunction

ubiquitin-proteasome system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease;

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Autophagy of the Nervous System

death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas;

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Resistance to Targeted Therapies in Multiple Myeloma

Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all;

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The Plasticity of Skeletal Muscle

in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome;

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Ubiquitin and Protein Degradation, Part B

of techniques. Second part of the Ubiquitin and Protein Degration series Topics include: E1 Enzymes, E2 Enzymes, E3 Enzymes;

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Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the;

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Modelling Proteasome Dynamics in a Bayesian Framework

Sabine Stubler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying;

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Cullin RING Ligases and Protein Neddylation

that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an;

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