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The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required;
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This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease. The editors and;
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The importance of the ubiquitin-proteasome system in cellular homoeostasis was emphasized by the award of the 2004 Nobel Prize in Chemistry;
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Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle;
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The ubiquitin-proteasome system (UPS) and ubiquitin-related modifiers are not only involved in cellular protein quality control but also;
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International Review of Cell and Molecular Biology, Volume 343 reviews and details current advances in cell and molecular biology. The;
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The last several years have been a landmark period in the ubiquitin field. The breadth of ubiquitin's roles in cell biology was first;
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proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway;
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encoded by the human genome comprise elements of the ubiquitin-proteasome system (UPS), making it the most complex of all biochemical pathways;
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length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to;
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Over the last decade, major advancements in our understanding of the ubiquitin-proteasome system (UPS) have occurred. This book focuses on;
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and proliferation. Cell cycle progression is driven by changes in the substrate specificity and subcellular localisation of cyclin-dependent;
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collection of cyclins, Cdk-activating and Cdk-inhibiting kinases, and Cdk inhibitors (CDKIs). Regulation of the cell cycle is critical for the normal;
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for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell;
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in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome;
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aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology;
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aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology;
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-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure;
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system, the blood cl- ting cascade, and the hormone-regulated remodelling of female reproductive tissues in adult mammals - proteolysis governs;
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editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and;
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Ubiquitin and Protein Degradation, Part B covers chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating;
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One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically;
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chemopreventors; natural products as inhibitors of ubiquitin and ubiquitin-like protein-proteasome pathways; the biological activities of red propolis;
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and linkage and genetic approaches to study the yeast ubiquitin system, amongst other timely topics ;
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A comprehensive and timely review of developments in the field, Cell and Molecular Biology of Stem Cell Imaging features original and;
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For courses in cell biology. Widely praised for its strong biochemistry coverage, Becker's World of the Cell, Eighth Edition Technology;
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; retroviral insertional mutagenesis; aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis; and epigenetic;
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Einde inhoud
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