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The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book;
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Oncogenes and tumour suppressor genes have been the focus of much research because of their role not only in cancer but also in normal cell;
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Contains papers and discussion from the June 1995 symposium, covering oncogene and tumor suppressor gene function, transcription regulation;
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of neutrophil function by tumour suppresser PTEN; the role of BRIT1/MCPH1 in genome maintenance and tumour suppression; epigenetic silencing of tumour;
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A tumour suppressor gene is a gene that reduces the probability that a cell in a multicellular organism will turn into a tumor cell. A;
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) becomes a tumour inducing agent, an oncogene. The protooncogene can become an oncogene by a relatively small modification of its original function;
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of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed;
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of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed;
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process and about the potential for controlling these malignant diseases. Molecular Genetics and Therapy of Leukemia presents contributions by;
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Oncogene proteins are proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene;
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oral cancer; tumour suppressor gene detection in oral tumours for new therapeutic strategy; innate immunity and oral carcinogenesis and;
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covered include discussions on how each metastasis suppressor was discovered, the mechanisms underlying their loss of expression in tumours and;
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Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are;
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of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from;
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of oncoproteins, including the cellular redox environment and oncongenestumour suppressors in breast cancer cells; cell surface oncoproteomics; site;
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lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so;
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The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an;
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development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression;
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understanding of cancer biology, out of which aberrations in oncogenes and tumour suppresser genes have arisen as important etiological factors;
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comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug;
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fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload;
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? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each;
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(tumour suppressor genes). The authors conclude the book with a review of current cancer research endeavors, looking ahead to possible future;
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of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the;
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