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Protein Instability at Interfaces During Drug Product Development

Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and;

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Protein Formulation and Delivery

product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage;

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Biophysics for Therapeutic Protein Development

theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters;

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Therapeutic Protein Drug Products

Therapeutic protein drug products provides a comprehensive overview of therapeutic protein drug products, with an emphasis on formulation;

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Protein-Protein Interactions

Michael D. Wendt Protein-Protein Interactions as Drug Targets Shaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev;

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Therapeutic Proteins

potential protein drug has been identified, the next rate-limiting step on the road to development is the production of sufficient authentic;

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Drug Product Development for the Back of the Eye

of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for;

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Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition

and regulatory concerns. Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition presents in-depth discussions from more;

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Protein-protein Complexes

focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are;

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Protein-protein Complexes

focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are;

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Protein Therapeutics

researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all;

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Protein Analysis using Mass Spectrometry

Development * Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery * Principles, Instrumentation;

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Phage Display In Biotechnology and Drug Discovery

in the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. The;

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Functional Selectivity of G Protein-Coupled Receptor Ligands

in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can;

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Current Progress in Drug Discovery and Development

. Drug development is the process of launching new drugs into the market after the lead compounds are identified during the drug discovery;

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Evaluation of Drug Candidates for Preclinical Development

sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost;

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Early Drug Development

drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the;

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Data Mining in Structural Biology

contributed to developments such as the production and expression of tailored protein domains, the use of the MAD (Multiple Anomalous Dispersion;

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Generic Drug Product Development

Generic Drug Product Development: Specialty Dosage Forms explores the issues related to providing evidence of pharmaceutical equivalence;

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Protein Surface Recognition

of functionality along extended patches of a protein surface with the aim of inhibiting proteinprotein interactions. The successful development;

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Protein and Peptide Mass Spectrometry in Drug Discovery

-assisted mass spectrometry, and recent applications, including pharmaceutical analysis throughout the drug development cycle. The book stresses;

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Generic Drug Product Development

Generic Drug Product Development: Specialty Dosage Forms explores the issues related to providing evidence of pharmaceutical equivalence;

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Protein Interactions as Targets in Drug Discovery

Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and;

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Hit and Lead Profiling

during the early drug development stages, using both in vitro and in silico methods. Both editors are based at one of the leading research-driven;

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The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols;

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Protein-Protein Interactions In Drug Discovery

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying;

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Computer Aided Drug Design

This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a;

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