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This book presents current research in the study of new technologies, developments and applications of microRNA and non-coding RNA. Topics;
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a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated;
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structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play;
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genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids;
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. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.;
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includes specific chapters on Non-coding RNAs as Biomarkers of Cancer, The Enigma of microRNA Regulation in Cancer, Animal Models to Study microRNA;
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Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for;
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functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on;
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of non-coding RNA and bone development, how 2) microRNAs and 3) long noncoding RNAs (LncRNAs) regulate bone formation, 4) how ncRNAs and the;
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This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their;
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regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic;
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diverse range of viruses, including positive and negative sense RNA viruses, DNA viruses, and a vector-borne virus. The roles of non-coding RNAs;
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There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than;
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RNA interference (RNAi) is a mechanism that inhibits gene expression by causing the degradation of specific RNA molecules or hindering the;
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applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly;
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in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA;
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in any of these processes, often caused by mutations in the coding and non--- coding RNAs, can be very destructive to the cellular environment;
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T and/or DC cell function, this extensive volume brings together the fields of coding (mRNA) and non-coding RNA such as ribozymes, RNAse P;
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Hybridization, non-coding RNAs, computational RNA biology, transcriptomes and bioinformatics, along with the latest advances in methods and protocols;
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MicroRNAs are small non-coding RNAs involved in post-transcriptional regulation of gene expression. Thousands of miRNAs have been;
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biology texts, adopting instead a modern approach in both concept and scope. The text is divided into three parts, on mRNA, non-coding RNA, and;
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Small non-coding RNA-dependent gene silencing is a highly conserved mechanism found in fungi, plants and animals. Drosophila melanogaster;
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and speed it offers. The small RNA molecules central to RNAi are microRNA (miRNA) and small interfering RNA (siRNA). These molecules bind to;
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examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current;
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offers a comprehensive view on our current understanding of these regulatory RNAs viz. siRNA, miRNA, piRNA, snoRNA, long non-coding RNA, small;
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time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the;
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This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging;
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