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Small non-coding RNA-dependent gene silencing is a highly conserved mechanism found in fungi, plants and animals. Drosophila melanogaster;
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study shown in Chapter 8 identified unique functions for DCL and RDR proteins in the diversification of small RNA pathways. Chapter 9 describes;
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small species of RNA. As an exciting new field of endeavor, it is the first book by a single author to deal comprehensively with RNA;
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and speed it offers. The small RNA molecules central to RNAi are microRNA (miRNA) and small interfering RNA (siRNA). These molecules bind to;
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functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on;
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; identification of RNA in analysis of body fluids stains for forensic purposes; cationic lipid-based nanoparticles for siRNA delivery; Interleukin-1;
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; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA;
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include methods and techniques for the isolation and quantitative/qualitative analyses of plant small 21-24 nucleotide RNAs such as small;
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RNA interference is a gene silencing phenomenon triggered by dsRNA (double-stranded RNA) and has been widely used for studying gene;
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Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at;
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brings together the pioneering work of researchers who discuss their work involving a wide variety of small RNA regulatory pathways in organisms;
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brings together the pioneering work of researchers who discuss their work involving a wide variety of small RNA regulatory pathways in organisms;
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respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states;
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Plant gene silencing is a crucially important phenomenon in gene expression and epigenetics. This book describes the way small RNA;
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chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs;
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of RNA interference to silence several genes that have opened up the use of siRNAs in the analysis of the various genes that are involved or;
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interesting chapters written by an international board of authors. Sections cover RNA modifications in viruses and virus infected cells, RNA silencing;
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including RNA silencing in transgenic plants and mycorrhizal research, gene silencing in the CNS and on the most extensively studied systems to;
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bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and;
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Plant Small RNA: Biogenesis, Regulation and Application describes the biosynthesis of small RNA in plant systems. With an emphasis on;
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The ability of plants to exchange RNA molecules and transcription factors between cells and tissues is a relatively recent discovery;
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provides pivotal information from the discovery of viroids through the analysis of their molecular and biological properties, to viroid;
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structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also;
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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA;
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sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA;
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invaluable avenue for therapeutics, and small interfering RNA (siRNA) is the most common strategy utilized for enacting RNAi. siRNA Design: Methods;
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