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for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook;
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for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook;
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in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as;
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as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many;
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.). Furthermore, potassium ion channels may be a target protein for the research and development of a therapeutic agent for various diseases concerning;
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This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the;
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Ion Channels, Part C, Volume 653 in the Methods in Enzymology series, highlights new advances in the field with this new volume;
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Ion Channels Part B, Volume 652 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting;
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Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and;
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Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel;
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critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different;
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treatment of diseases of skeletal muscles, including the muscular dystrophies, mitochondrial myopathies, metabolic myopathies, ion channel disorders;
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Ion channels generate bioelectricity. Recent findings have documented the biophysical properties, the structure, assembly and regulation;
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developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors;
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Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single;
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The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel;
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, physicochemical properties, and biological activity.In a set of four interrelated volumes, The Ion Channel FactsBook provides a comprehensive;
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This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental;
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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has;
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in engineering systems. These geometries include a straight flow channel, a constricted channel, a channel with a roughened surface, a channel with a;
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ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new;
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neuroscience of perception, and ion channel mechanisms.;
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Ion Channels Part A, Volume 651 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting;
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of an array of human diseases. Mutations associated with the cardiac sodium channel are responsible for a wide spectrum of disorders. The;
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Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium;
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about proteins but were too busy to look for. In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive;
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The rapid growth of interest and research activity in ion channels is indicative of their fundamental importance in the maintenance;
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