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This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the;
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Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium;
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This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and;
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Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium;
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Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part B, Volume 603, presents a coherent description of the;
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on the experience of eminent researchers in the field. Interest and investment in ion channel modulation in both industrial and academic;
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Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A, Volume 602 assembles new information on our;
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-Gated Channels; Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function; Pharmacology of Hair Cell MS Channels; Hair;
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evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section;
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. There are many types of potassium ion channels (voltage-gated K+ channels, ATP-sensitive K+ channels, Ca2+-activated K+ channels, etc.), and;
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Calcium channels are ion channels which display selective permeability to calcium ions and are sometimes synonymous as voltage-dependent;
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+ signaling, TRPML channels in coronary vascular phenotypic modulation and calcification, Local voltage-gated Ca2+ channel regulation of vascular;
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channels and neuronal function.* Brings together both the basic biology and biophysics with detailed consideration of the medical applications;
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of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an;
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in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as;
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membrane in an excitable cell (such as a neuron or myocyte) generated by the activity of voltage-gated ion channels embedded in the membrane. The;
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of receptors, and responses downstream from receptor activation. More light is thrown on ligand-gated ion channels and G protein-coupled receptors;
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Transduction: Structure and Function of Mechanosensitive Channels in Prokaryotes; Activation of Mechanosensitive Ion Channels by Forces Transmitted;
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, and function and dysfunction of nonclassical nervous system ion channels. This book reviews nonclassical ion channel research, ranging from;
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-splicing, Probing Ion Channel Neighborhoods Using APEX, STX based probes for NaVs, ANAP: a versatile, fluorescent probe of ion channel gating and;
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of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function;
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includes DPLC equipment use in digital transmitting systems, including digital modulation and coding, channel equalization, and echo cancelling;
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includes DPLC equipment use in digital transmitting systems, including digital modulation and coding, channel equalization, and echo cancelling;
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in arthropods. The development of chemical insecticides has primarily attacked the arthropod nervous system by targeting and disrupting the function;
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Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and;
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This volume looks at the methodology and techniques used by experts to study how certain molecules function in specific locations, and;
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and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters * Covers state-of-the art analytical;
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