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Experimental Design and Reproducibility in Preclinical Animal Studies

, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies;

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The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols;

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Statistical Challenges in Assessing and Fostering the Reproducibility of Scientific Results

contribute to the lack of perfect reproducibility, including insufficient training in experimental design, misaligned incentives for publication and;

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Animal Models for Microbiome Research: Advancing Basic and Translational Science

Research 4 Modeling Human Microbiota in Animal Systems 5 Experimental Reproducibility Using Gnotobiotic Animal Models 6 Establishing and;

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Cellular Signal Transduction in Toxicology and Pharmacology

involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis;

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Using Animal Models In Biomedical Research

information on bioimaging, occupational health and biosafety, animal protocol design and histological-pathological support.;

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Experimental Models of Infection, Inflammation and Injury

Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to;

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Nonclinical Study Contracting and Monitoring

preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and;

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Image Fusion in Preclinical Applications

of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and;

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Preclinical Drug Disposition

, distribution, metabolism, and excretion of test compounds using laboratory animals. Describes types of experiments, study design, animal preparation;

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Reproducibility in Biomedical Research

explorations a valuable addition to their libraries. Considers the meaning and purpose of reproducibility to help design research

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Quantitative Pharmacology

analysis Introduces the principles behind different biomarkers and inter-species scaling Discusses experimental design of PK, PD and safety;

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Preclinical Drug Development

Screening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic;

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Bioassays in Experimental and Preclinical Pharmacology

drugs and their development through in vitro, involving tissues and cell lines, and in vivo models, using animals as experimental systems;

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Handbook of Small Animal Imaging

The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to;

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. This fact has been established by numerous laboratory and epidemiological studies, however, the physical nature of the phenomenon is still not;

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Animal Models Of Neuropsychiatric Diseases

Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological;

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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog.

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Histopathology of Preclinical Toxicity Studies

The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the;

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Animal Models of Diabetes

and comprehensive, Animal Models of Diabetes: Methods and Protocols is a valuable resource that will help diabetes researchers design and;

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Translational Biology in Medicine

experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental;

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The Design of Animal Experiments

Covers all randomised controlled experimental designs likely to be needed in laboratory animal research, with worked examples showing how;

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Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences

Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences A practical guide to the use of basic principles;

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Design and Analysis of Animal Studies in Pharmaceutical Development

Provides well-integrated, comprehensive coverage of all the major statistical designs and methods used for animal studies in pharmaceutical;

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Research in the Biomedical Sciences

in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent;

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The Laboratory Rat

important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental;

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The Laboratory Rat

important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental;

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