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Constitutive Activity in Receptors and Other Proteins, Part A

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins;

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Constitutive Activity in Receptors and Other Proteins, Part B

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins;

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G ProteinCoupled Receptors as Drug Targets

researchers into the advances in the understanding of GPCR activation and constitutive activity. In addition, the book provides an overview on methods;

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Revival

science, cancer therapy, and other diseases. The chapters provide multiple viewpoints of the emerging data on AP-1, including its role as a factor;

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G Protein Coupled Receptor Dimers

healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.;

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Revival: The FOS and JUN Families of Transcription Factors (1994)

science, cancer therapy, and other diseases. The chapters provide multiple viewpoints of the emerging data on AP-1, including its role as a factor;

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Signaling By Receptor Tyrosine Kinases

. Ligand binding stimulates the tyrosine kinase activity of the receptors, leading to recruitment of enzymes and adapter proteins that activate;

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G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review;

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G Protein-Coupled Receptors

receptors respond to a wide variety of structurally diverse ligands, ranging from small molecules, such as biogenic amines, nucleotides and ions, to;

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G Protein-Coupled Receptors - Part A

G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new;

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G Protein Pathways, Part B: G Proteins and Their Regulators

This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by;

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Amino Acid Receptor Research

Amino acid receptors and cell surface proteins that bind amino acids and trigger changes which influence the behaviour of cells. Glutamate;

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Neuropeptide Receptors

Neuropeptides mediate their effects by binding and activating receptors that are responsible for converting these extracellular stimuli;

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Endothelin Receptors

in detail, as well as the roles that they may play a part in the physiologic and pathophysiologic processes in animals and in humans. This book;

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Towards a Normative Theory of International Relations

implicitly accepted) for ignoring moral theory and finds that none of them stands up to close scrutiny. In Part Two a start is made towards the;

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Regulation Of G Protein Coupled Receptor Function And Expression

providing a basis and means for manipulating receptor function through multiple intracellular targets. This volume covers methods used to examine;

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General Principles and Procedures

others. This com monality is in part substantive, and in part practical and procedural. Substantively, the receptors are all macromolecules;

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Nucleic Acid Sensors and Antiviral Immunity

the role of TLR4 in the response to LPS). Work on TLRs inspired many researchers, and led to a search for other receptors in innate immunity;

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Novel Biosensors Using Intact Liposome Microarrays

membrane bound.Naturally, there is a great interest in development of sensors using membrane proteins for drug discovery and high-throughput;

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A Closer Look at Membrane Proteins

This book opens with a description of the insulin-like growth factor system, with focus on the insulin-like growth factor receptors and;

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Molecular Design and Modeling: Concepts and Applications, Part A: Proteins, Peptides, and Enzymes

Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein;

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Chemokines, Chemokine Receptors and Disease

, in normal and disease-related states. Chemokines are small proteins that are important in normal immune responses. Recent research demonstrates a;

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Affinity And Efficacy: The Components Of Drug-receptor Interactions

to measure the affinity and efficacy of drugs through the analysis of single receptor activity, the activation state of a population;

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Protein Reviews Purinergic Receptors

The Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein;

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Protein Reviews - Purinergic Receptors

The Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein;

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Death Receptors and Cognate Ligands in Cancer

initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical;

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Adenosine Receptors in Health and Disease

expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including;

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Einde inhoud

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